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1221 deaths

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Saint Dominic
founder of the Dominican Order (1170–1221)
Theodore I Laskaris
13th-century emperor of Nicaea
Muhammad II of Khwarazm
Soltan of Khwarezm Empire (1200–1220)
Berengaria of Portugal
Queen of Denmark (1198-1221)
Gebre Mesqel Lalibela
Ethiopean Emperor
Alix, duchess of Brittany
Hereditary Duchess of Brittany 1203-1221, Breton noble
Najmuddin Kubra
Iranian sufi poet and philosopher
Theodoric I
Margrave of Meissen
Henry III, Duke of Limburg
Duke of Limburg and Count of Arlon
Abraham of Smolensk
a Russian monk and priest
Mutukan
Mutukan also spelled as '''Mö'etüken''' (died 1221), was the eldest son of Chagatai Khan and a grandson of the founding Mongol khagan Genghis Khan. Mutukan was killed during the siege of Bamyan in 1221 by an arrow from the besieged walls. His son was Yesü Nto'a. Yesu' Nto'a was the father of Baraq (Chagatai Khan). Buraq Khan was the khan of Moghulistan from 1266 to 1271.
Jalal al-Din Hassan III
Nizari Imam of Alamut
William IV, Count of Ponthieu
Count of Ponthieu
Nicholas of Ajello
Italian priest
Henry I of Rodez
Count of Rodez and Viscount of Carlat from 1208 until his death
Roger Bigod, 2nd Earl of Norfolk
English diplomat and royal steward
Adam of Perseigne
French Cistercian abbot
Abu-Muhàmmad Abd-al-Wàhid ibn Abi-Hafs
Almohad governor of Ifriqya from 1207 to 1221
Qutb ad-Din Haydar
Persian saint
Arnold III, Count of Loon
count of Loon
Rambertino Buvalelli
Italian poet, judge and statesman
Robert de Vere, 3rd Earl of Oxford
hereditary Master Chamberlain of England
Conrad of Eberbach
Cistercian monk, abbot and monastic historian
Raoul de Neuville
cardinal