1421 births

King of England from 1422 to 1461 and from 1470 to 1471, disputed King of France from 1422 to 1453

King of Navarre

Italian humanist writer and gastronomist (1421–1481)

Italian banker, younger son of Cosimo de Medici (1421-1463)

English noble

Italian humanist

thumb|A print (by Tsukioka Yoshitoshi) depicts Sōgi writing a couplet for a ghost. Iio Sōgi, (or Inō Sōgi) generally known as , was a Japanese poet. He came from a humble family from the province of Kii or Ōmi, and died in Hakone on September 1, 1502. Sōgi was a Zen monk from the Shōkoku-ji temple in Kyoto and he studied poetry, both waka and renga. In his 30s, he became a professional renga poet.

natural son of Philip III, Duke of Burgundy and Jeanne de Presle (1421-1504)

Count of the Kingdom of Navarre

Electress of Brandenburg

Walloon knight (1421-1453)

Italian banker

Greek painter (1421-1492)

Chinese politician during the Ming dynasty