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1481 deaths

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Mehmed II
seventh Sultan of the Ottoman Empire (1444–1446, 1451–1481)
Christian I of Denmark
Scandinavian monarch under the Kalmar Union (1426-1481)
Afonso V of Portugal
King of Portugal and the Algarves
Jean Fouquet
French painter (c. 1420–1481)
Luca della Robbia
Italian sculptor (1399–1482)
Ikkyū Sōjun
thumb|right|240px|Buddhist verse by Ikkyū
Axayacatl
thumb|500px|Map showing territorial expansions of the Aztec Empire under each of the Aztec rulers. Expansions during the reign of Axayacatl are indicated in blue.
Francesco Filelfo
Italian Renaissance humanist (1398–1481)
Bartolomeo Platina
Italian humanist writer and gastronomist (1421–1481)
Ahmed Khan bin Küchük
Khan of the Great Horde
Agostino di Duccio
Italian artist (1418–1481)
Afonso Gonçalves Baldaia
Portuguese explorer (14__-1481)
John I, Duke of Cleves
Duke of Cleves and Count of Mark (1419-1481)
Charles IV, Duke of Anjou
French noble
Barbara of Brandenburg
Marchioness of Mantua
Karamani Mehmet Paşa
Ottoman grand vizier (1458–1481)
Anne Mowbray, 8th Countess of Norfolk
English noblewoman (1472–1481)
Narsinh Mehta
poet-saint of Gujarat
Erik Axelsson Tott
Regent of Sweden (1419-1481)
Mahmud Gawan
Iranian poet
Guiniforte Solari
Italian artist (1429-1481)
Sunan Ampel
Indonesian Wali Sanga Islamist
Ichijō Kaneyoshi
Court noble
Teodoro Paleologo di Montferrato
Italian cardinal
Juan de Colonia
German architect
Chakkaphat Phaen Phaeo
King of Lan Xang
Sano di Pietro
Italian painter (1405–1481)
Cosma Orsini
Italian cardinal
Amalie of Brandenburg
Countess Palatine and Duchess of Zweibruecken and Veldenz (1461–1481)
Asakura Takakage
7th head of Asakura clan. daimyo of the middle Muromachi period. a.k.a. Eirin
Françoise of Châtillon
French aristocrat
Mikhailo Olelkovich
Lithuanian noble
Gö Lotsawa Zhönnu-pel
Tibetan historian
Juan Rejón
Spanish explorer
Nicolò Malermi
biblical scholar
Giovanni Solari
Architect and engineer
Jonas I Losovičius
Lithuanian Roman Catholic Bishop of Lutsk and later Bishop of Vilnius
Kuai Xiang
Chinese architect and engineer
Giulio Antonio Acquaviva
Italian noble and condottiere
Euphrosynus of Pskov
Russian monk and saint
Giovanni di Paolo Rucellai
Renaissance humanist, grandfather of Giovanni di Bernardo Rucellai
Charles I d'Amboise
French politician and military figure (1430-1481)
Mary Woodville
Countess of Pembroke; younger sister of Elizabeth Woodville
Johann Ruchrat von Wesel
German scholastic theologian