1546 deaths

German priest and theologian (1483–1546)

Turkish admiral (1478–1546)

Spanish explorer and conquistador

Italian painter and architect (1499–1546)

Spanish philosopher

Jesuit priest and evangelist

Italian architect (1484–1546)

Spanish explorer (1500-1546)

voievod of Moldavia

French translator and scholar (1509-1546)

Catholic cardinal (1494-1546)

Prince of Lüneburg-Celle

English Protestant martyr

Italian painter (1475–1546)

Catholic cardinal

Greek orthodox saint-Patriarch of Constantinople

English politician and writer (1490-1546)

Spanish-Italian nobleman; Governor of the Duchy of Milan

First viceroy of Peru (1490-1546)

French military leader (1519-1546)

Catholic cardinal

Scottish Protestant martyr; (1513-1546)

daughter of Duke Frederick II

German explorer

Italian cardinal

Italian painter (1505-1546)

Spanish conquistador

15th- and 16th-century French printer, editor, and publisher during the Renaissance

German theologian

Chairachathirat (, ), or Chai was from 1534 to 1546 the King of Ayutthaya, an ancient kingdom in Thailand. His reign was notable for the increasing presence of Portuguese traders, soldiers, and the introduction of firearms and other modern military technologies to Siam. thumb|Ayutthaya during Chairacha's reign Chairachathirat ascended the throne following the short reign of King Ratsadathirat, and ruled during a period of internal consolidation and growing foreign contact. His court maintained relations with the Lan Xang and Lanna kingdoms, while also contending with Burmese incursions from To

Roman Catholic archbishop (1458-1546)

Doge of the Republic of Genoa

Japanese samurai

Third Emperor of the Mạc dynasty

rabbi and kabbalist

Spanish sailor

Korean philosopher

Irish Earl; (1496-1546)

Sayyidi ʻAbd al-Raḥmān ibn Muḥammad al-Ṣaghīr ibn Muḥammad ibn Sayyidi ʿĀmir al-Akẖḍarī al-Bīsīkrī Arabic :سيدي عبد الرحمن بن محمد الصغير بن محمد بن سيدي عمرو الأخضري, better known as Al-Akẖḍari (), born in 1512 in Biskra in present-day Algeria and died in 1575 in Biskra in present-day Algeria, was an Arab poet, logician, astronomer and maliki jurist.

Italian artist (1468-1546)

Italian politician

Swiss composer

Damascene scholar (1475–1546)

Spanish explorer (1509-1546)

court noble of the late Muromachi period

Spanish noble

lady of the Sengoku period

Spanish explorer