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1580 births

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Francisco Quevedo
Spanish writer (1580-1645)
John Smith
English soldier, explorer, writer (1580–1631)
Jan Baptist van Helmont
chemist, physiologist, and physician from the Spanish Low Countries
Willebrord Snellius
Dutch astronomer and mathematician
Gabriel Bethlen
Elected King of Hungary, Prince of Transylvania and Hungarian Protestant military leader (1580–1629)
Nicolas-Claude Fabri de Peiresc
French astronomer (1580–1637)
Thomas Middleton
English playwright and poet
Peter Claver
Jesuit missionary
Dirk Hartog
Dutch explorer
Augusta of Denmark
duchess consort of Schleswig-Holstein-Gottorp
Charles Gonzaga, Duke of Mantua and Montferrat
duke of Mantua and Montferrat (1580–1637)
António de Andrade
Portuguese Jesuit priest, missionary, and explorer (1580–1634)
Pierre Vernier
French mathematician
Carlo Contarini
Doge of Venice (1580-1656)
Philipp Clüver
German geographer and historian (1580–1622)
Daniel Heinsius
Dutch scholar and poet (1580-1655)
Johann Faulhaber
German mathematician
Bogislaw XIV, Duke of Pomerania
Duke of Pomerania-Rügenwalde, then all of Pomerania
Elisabeth Magdalena of Pomerania
German duchess consort of Courland (1580-1649)
Gaspar de Borja y Velasco
Spanish cardinal, ecclesiastic and politician (1580-1645)
Cristóvão Ferreira
Portuguese Jesuit missionary
Pierre Hérigone
French astronomer
Ling Mengchu
Chinese writer of the Ming Dynasty
Oda Hidenobu
the son of Oda Nobutada and lived during the Azuchi-Momoyama period in the late-16th century
Matsudaira Tadayoshi
[松平忠吉] son of Tokugawa Ieyasu
Marco Aurelio Severino
Italian scientist
Elisabeth of Schleswig-Holstein-Sonderburg
Duchess consort of Pomerania
George Calvert, 1st Baron Baltimore
English peer and politician (1580–1632)
Peter Crüger
German astronomer and mathematician (1580-1639)
Countess Charlotte Brabantina of Nassau
Dutch noble (1580-1631)
Adriaen van Stalbemt
Flemish Baroque painter (1580-1662)
George Percy
Colonial Governor of Virginia
Francisco Rodrigues Lobo
Portuguese writer 1580 - 1622
William Herbert, 3rd Earl of Pembroke
English Earl (1580-1630)
Godfried Wendelen
Flemish astronomer
Francesco Mochi
Italian sculptor (1580-1654)
Gundakar, Prince of Liechtenstein
Court official in Vienna (1580-1658)
Pèire Godolin
poet
Grandprince Jeongwon
Prince of Joseon Dynastys (1580-1619)
Nabeshima Katsushige
daimyo
Pedro Orrente
Spanish artist (1580-1645)
Kho Orluk
17th-century Taish of the Torghut-Oirat tribe
Ivan Tomko Mrnavić
Croatian bishop and writer
Charlotte des Essarts
French aristocrat (1580-1651)
Orazio Giustiniani
Catholic cardinal (1580-1649)
Hortensio Félix Paravicino
Spanish monk and writer (1580-1633)
John Digby, 1st Earl of Bristol
English diplomat
Henri Duval de Dampierre
Francesco Adriano Ceva
Roman Catholic cardinal
Giovanni Battista Deti
Italian cardinal and bishop
Willem Jacobsz Delff
painter from the Northern Netherlands (1580–1638)
Cuyen
Cuyen (; 1580 – 14 October 1615) was a Manchu prince and eldest son of the Later Jin ruler Nurhaci, the early patriarch of the Qing dynasty. An accomplished warrior, Cuyen was instrumental in the consolidation of Nurhaci's authority among rival Jurchen clans. He also served as the primary civil administrator for intermittent periods in the regime founded by Nurhaci. However, he eventually lost favour with his father because he tried to cast sorcery spells against other princes. He was placed in solitary confinement and died in captivity a few years later.
Manuel de Almeida
Christian missionary
Dietrich von Falkenberg
German statesman
Mar'i al-Karmi
Islamic scholar
Francisco de Lugo
Spanish Jesuit theologian (1580-1652)
Raphael Sobiehrd-Mnishovsky
Czech writer
Szymon Okolski
Polish historian
Hans Nielsen
composer
Aleksander Słuszka
Lithuanian noble