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15th-century births

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Mimar Sinan
16th-century Ottoman chief architect and civil engineer
François Rabelais
16th-century French writer and humanist (1494–1553)
Hayreddin Barbarossa
Turkish admiral (1478–1546)
Pietro Perugino
Italian Renaissance painter of the Umbrian school (1448-1523)
Niccolò Tartaglia
Italian mathematician (1499–1557)
Aldus Manutius
Italian printer and humanist (1449-1515)
Sher Shah Suri
Founder of the Suri Empire in India (1472-1545)
Johannes Ockeghem
Franco-Flemish composer
Álvar Núñez Cabeza de Vaca
Spanish explorer of the New World
Francysk Skaryna
Ruthenian humanist, bible translator and book printer
Antonio del Pollaiuolo
Italian painter, sculptor and engraver (1429-1498)
Huayna Capac
13th Inca Emperor
Veit Stoss
German sculptor (1447–1533)
Johann Georg Faust
German Renaissance alchemist, astrologer, and magician
Ahuitzotl
250px|thumb|Map showing the expansion of the Aztec Triple Alliance. The conquests of Ahuitzotl are marked in yellow.
Sebastián de Belalcázar
Spanish conquistador
Jacopo de' Barbari
Italian painter and engraver (1460-1516)
Diego Columbus
Spanish governor of the Indies and son of Christopher Columbus
Hōjō Sōun
Japanese daimyo of the early Sengoku period
Pedro Mascarenhas
Portuguese explorer and colonial administrator
Bernard van Orley
Flemish draughtsman, painter (c.1488-1541)
Rodrigo de Bastidas
Spanish conquistador
Stephen Thomas of Bosnia
Bosnian king
Hatuey
thumb|right|Monument of Taíno chief Hatuey in Yara, Cuba|Yara city, depicting the moment he was burnt by Spanish soldiers, bound to a [[tamarind tree planted in 1907.]] thumb|right|alt=Stone slab with an embossed inscription in Spanish, for which refer to the caption.|Plate at the base of the monument. It reads "To the memory of Chief Hatuey, the unforgettable Indian, precursor of Cuban liberty who offered his life and glorified his rebellion in martyrdom by flames on February 2, 1512. Monuments Delegation of Yara, Cuba|Yara, 1999".
Duarte Barbosa
Portuguese explorer and writer (1480–1521)
Mesih Pasha
Ottoman admiral and statesman
Caspar Schwenckfeld
German theologian
Alvise Vivarini
Venetian painter (15. century)
James II of Cyprus
King of Cyprus, Jerusalem and Armenia
Jorge Álvares
Portuguese explorer
Francisco de Bobadilla
Spanish conquistador and colonial governor
Despina Khatun
Princess of Trebizond
Koca Davud Pasha
Albanian general and grand vizier of the Ottoman Empire from 1482 to 1497
Badi' al-Zaman Mirza
Timurid monarch
Francisco Serrão
Portuguese explorer
Abdallah Mirza
ruler of the Timurid Empire
Juan de Bermúdez
Spanish explorer
Ludwig I, Count of Württemberg-Urach
German nobleman
Catherine of Bjurum
Queen consort of Sweden from 1448 to 1450 and later the Queen consort of Norway from 1449 to 1450. She was the second wife of Charles VIII of Sweden, I of Norway.
Jacob Cornelisz van Oostsanen
Dutch painter and designer of woodcuts (before 1470-1533)
Nicolas Chuquet
mathematician
Eric II, Duke of Pomerania
Duke of Pomerania-Wolgast
Ambrosius Benson
Italian painter (c.1500-1550)
Elizabeth of Nevers
Duchess of Cleves by marriage
David X of Kartli
King of Kartli
Adriaen Isenbrandt
Early Netherlandish painter (c. 1495-1551)
Hadim Ali Pasha
Ottoman governor of Rumelia, Grand Vizier, and leader of the Ottoman army in the Ottoman–Mamluk War of 1485–1491
Jan Joest
painter
Jeremias I of Constantinople
Greek orthodox saint-Patriarch of Constantinople
Georges Chastellain
Burgundian writer and historian
Arnolt Schlick
German composer (1460–1525)
Gianfrancesco Penni
Italian painter (1488-1528)
Giovanni Battista Zeno
Italian cardinal
Anna Notaras
Greek printer (died 1507)
Juan de Ayolas
Spanish conquistador and explorer
Hermen Rode
German artist (fl. 15th century)
Helena Kantakouzene, Empress of Trebizond
second wife of Emperor David of Trebizond
Bonifacio Bembo
Italian painter and miniaturist of the early-Renaissance (1420-1480)
Costanzo Festa
Italian composer
Bogislaw IX, Duke of Pomerania
duke of Pomerania in Pomerania-Stolp