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1621 deaths

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Paul V
233rd pope of the Roman Catholic Church from 1605 to 1621
Philip III of Spain
King of Castilla and León and King of Aragon and Portugal (1578-1621)
Robert Bellarmine
Catholic cardinal, saint, and Doctor of the Church
Thomas Harriot
British scientist (*~1560 – †1621)
Michael Praetorius
German composer, organist, and music theorist
Cristofano Allori
Italian portrait painter of the late Florentine Mannerist school (1577-1621)
Jan Pieterszoon Sweelinck
Dutch composer, organist, and pedagogue in the Renaissance-Baroque eras
Albert VII, Archduke of Austria
Austrian cardinal and governor of the Netherlands (1559-1621)
Cosimo II de' Medici
Grand Duke of Tuscany (1590-1621)
Ambrosius Bosschaert
Flemish-Dutch flower painter (1573-1621)
Jan Karol Chodkiewicz
army commander of the Grand Duchy of Lithuania (1560-1621)
Johann Arndt
German Lutheran theologian (1555-1621)
John Berchmans
Catholic Jesuit saint
Bahāʾ al-dīn al-ʿĀmilī
Iranian Shia Islamic scholar, philosopher, architect, mathematician, astronomer and poet
Dirk Hartog
Dutch explorer
Antoine de Montchrestien
French economist and dramatist
Catherine Stenbock
Queen Consort of Sweden (1535-1621)
Hendrick de Keyser
Dutch architect (1565-1621)
Ottavio Rinuccini
Italian poet (1562-1621)
Pietro Aldobrandini
Catholic cardinal (1571-1621)
Mary Sidney
Countess of Pembroke, poet, and literary patron
Princess Maria Christina I, Princess of Transylvania
Princess Consort of Transylvania and Austrian archduchess (1574-1621)
Charles d'Albert de Luynes
duke of Luynes
Şehzade Mehmed
son of Ottoman Sultan Ahmed I and Kösem Sultan
Jan Jesenius
Bohemian philosopher, doctor, politician and science writer (1566-1621)
Anna Juliana Gonzaga
Italian-born Archduchess of Austria and Religious Sister
Rudolph, Prince of Anhalt-Zerbst
Prince of Anhalt, then Prince of Anhalt-Zerbst (1576-1621)
Charles Bonaventure de Longueval, Count of Bucquoy
military commander (1571-1621)
John Barclay
Scottish writer
Güzelce Ali Pasha
Ottoman Kapudan Pasha and Grand Vizier
Guillaume du Vair
French bishop, Magistrate of the Parliament, Keeper of the Seals of France under Louis XIII
Edward Seymour
1st Earl of Hertford (1539-1621)
Henry of Lorraine, Duke of Mayenne
French noble (1578-1621)
Francesco Soriano
Italian composer of the Renaissance, born 1548 or 1549, died 29 July 1621 (1549–1621)
Blessed Anne of Jesus
Spanish Discalced Carmelite nun and spiritual writer (1545-1621)
Diane d'Andoins
French noblewoman
Asmat Begum
John Carver
Mayflower passenger and New World colonist
Anne of Ostfriesland
German noblewoman (1562-1621)
Don Giovanni de' Medici
Italian military commander and diplomat (1567-1621)
Louis III of Lorraine, cardinal of Guise
Catholic cardinal (1575-1621)
Antonio de' Medici
Italian noble (1576-1621)
William Strachey
English writer
Rudolph Goclenius the Younger
German physician and professor of physics, astronomy and arithmetic
Dorothea of Lorraine
Peerage person ID=7681
Benedetto Giustiniani
Catholic cardinal
Ambrogio Doria
Dodge of the Republic of Genua
Pierre Matthieu
French writer, poet, historian and dramatist (1563-1621)
Andrzej Sapieha
Polish-Lithuanian nobleman
Charles II de Cossé, Duke of Brissac
Marshal of France
Kryštof Harant
Czech traveller, composer and writer (1564-1621)
Nizamuddin Ahmad
historian
Louis de Caullery
Flemish painter (1580-1621)
Joachim Andreas von Schlick
Czech nobleman (1569-1621)
Giacomo Sannesio
Italian Catholic cardinal
Anne de Xainctonge
French saint
Muhammad al-Munawi
'''Muhammad 'Abd al-Ra'uf al-Munāwi (), also known as Al-Munāwi''' () was an Egyptian Islamic scholar of the Ottoman period. He was a prominent Shafi'i jurist, hadith specialist, historian, and sufi mystic. He is considered one of the most greatest Sunni scholars and prolific writers of his time. His most celebrated work, Fayd al-Qadir, stands as a cornerstone of classical Islamic scholarship. He was the paternal great-grandson of Sharaf al-Din al-Munawi and was the famous disciple of Al-Sha'rani.
Claud Hamilton, 1st Lord Paisley
Scottish politician and noble
Abd al-Aziz al-Fishtali
Moroccan state official and poet (1549–1621)
Rodrigo Calderón, Count of Oliva
First Minister of Spain