16th-century deaths

last Nasrid ruler of Grenada

Spanish explorer of the New World

Spanish navigator, explorer

Portuguese explorer and diplomat

Flemish Renaissance painter

Regent of the Kazan Khanate (1516-1557)

Portuguese Jewish philosopher, physician and poet

German painter and engraver

French tragic poet

French artist (1510–1567)

Portuguese apothecary and diplomat

medieval Scottish poet and civil servant

French mathematician

painter (1500/1510-1555)

Spanish composer, vihuelist

French composer

Polish writer

Italian painter (ca. 1490-1543)

16th-century Safavid historian and military officer

German artist (fl. 15th century)

or , baptized as Paulo de Santa Fé, was the first recorded Japanese Christian, who lived in the 16th century. After committing a murder in his home domain of Satsuma in southern Kyushu, he fled to Portuguese Malacca and he sought out Saint Francis Xavier (1506–1552) and returned to Japan with him as an interpreter. Along with Xavier, Anjirō returned to Japan with two other Jesuits, two Japanese companions, and a Chinese companion who had been baptized to Catholicism to form the first Jesuit mission to Japan.

chronicler

Italian philosopher

samurai in Japan's Sengoku period

Patriarch of Constantinople

French artist (1485–1561)

German sculptor (15./16. century)

French writer and translator

Croatian historian

Portuguese nobleman and colonial officer

Spanish composer

painter (1440-1515)

Portuguese composer

Greek historian

Croatian writer (16th century)

Italian nun

Franco-Flemish composer

Italian painter (1465-1527)

Franco-Flemish composer

daughter of Catherine Parr

Italian composer, lutenist and nobleman

Italian painter (1474-1540)

Portuguese astronomer, astrologist, and writer

painter

Portuguese marrano Jewish author

Italian painter (1477-1533)

Italian philosopher

Polish composer

artist from Italy (1460-1520)

Spanish conqueror and politician (1541–1501)

Early Netherlandish painter

German artist (c.1450-c.1510)

nun

German painter (active between 1480–1520)

Florentine government clerk

Doge of the Republic of Genoa

Countess of Bar-sur-Seine/Dame de Givry/Baroness of Pagny/Mirebeau/illegitimate half-sister of King Francis I/France

Malian historian

Italian writer (1475-1533)

Italian painter and medalist