16th-century deaths from plague (disease)

Tiziano Vecellio (; 27 August 1576), Latinized as Titianus, hence known in English as Titian ( ), was an Italian Renaissance painter. The most important artist of Renaissance Venetian painting, he was born in Pieve di Cadore, near Belluno.

German artist and printmaker (1497–1543)

Giorgio Barbarelli da Castelfranco (; 1470s – 17 September 1510), known as Giorgione, was an Italian painter of the Venetian school during the High Renaissance, who died in his thirties. He is known for the elusive poetic quality of his work, though only about six surviving paintings are firmly attributed to him. The uncertainty surrounding the identity and meaning of his work has made Giorgione one of the most mysterious figures in European art.

Italian Renaissance painter of the Umbrian school (1448-1523)

Italian painter (1486-1530)

Swiss physician, bibliographer and naturalist (1516–1565)

Italian painter (1462–1522)

Mother of King Francis I of France (1476-1531)

Flemish composer

Netherlandish composer

painter who worked in Tallinn (1459-1525)

German theologian (1480 ca-1541)

1455-1505, Italian Cardinal of the Catholic Church

Hungarian musician (ca. 1506-1576)

Spanish composer of the Renaissance

Italian military engineer (1521-1570)

Scottish churchman, scholar, poet

Swiss orientalist and linguist

English noblewoman (1545?–1578)

Marshal of France

Italian saint, Clarissa, mystic and humanist (1548-1524)

Catholic cardinal (1465-1522)

German astronomer

German academic

German Catholic bishop and theologian

Italian painter (1480-1528)

mother of Gustav Vasa

Spanish Protestant Bible translator

Portuguese Dominican friar and travel writer (c.1520–1570)

German theologian and Anabaptist leader (1495-1527)

Dutch doctor and mathematician (1520-1564)

Czech lawyer and writer

French Hebraist (c.1515-1570)

thumb|Quoniambebe as depicted on the pages of The [[Revista do Instituto Histórico e Geográfico Brasileiro|Journal of the Brazilian Institute of History and Geography from André Thevet's La Cosmographie Universelle published thirty years before the example below.]]

Italian printer (fl. 1550-1582)

French printer, book publisher and bookseller (1504-1564)

physician, editor of Paracelsus

German Reformer & hymnwriter (1496–1542)

Protestant reformer

Bishop of Urgel, Viceroy of Catalonia and Archbishop of Tarragona

Mother-in-law of King Gustav I of Sweden

wife of three religious reformers

Belgian composer

Italian bishop

Transylvanian Saxon poet

15th/16th-century English classical grammarian and scholar (1468–1522)

son of Titian (1528-1576)

German theologian