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16th-century Italian nobility

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Catherine de' Medici
queen-consort and regent of France (1519–1589)
Lucrezia Borgia
Spanish-Italian duchess-consort of Ferrara, Modena and Reggio (1480-1519)
Ludovico Sforza
duke of Milan
Cosimo I de' Medici, Grand Duke of Tuscany
Duke of Florence
Bona Sforza
Queen of Poland and Grand Duchess of Lithuania
Ferdinando I de' Medici
Grand Duke of Tuscany (1549-1609)
Isabella d'Este
Italian noble
Caterina Sforza
Lady of Imola and Countess of Forlì (1463-1509)
Lorenzo de' Medici, Duke of Urbino
Italian noble (1492-1519)
Francesco I de' Medici
Grand Duke of Tuscany (1541-1587)
Vittoria Colonna
Italian poet and noble
Bianca Maria Sforza
Holy Roman Empress, Presumptive crown princess of Hungary
Anne of Bohemia and Hungary
Queen Consort and Princess of Hungary and Bohemia, Queen Consort of Germany and Archduchess of Austria
Margaret of Parma
Habsburg noble (1522-1586)
Alessandro de' Medici
Duke of Florence (1510-1537)
Ercole I d'Este
Duke of Ferrara from 1471 to 1505
Vincenzo Gonzaga
Duke of Mantua and Montferrat (1562-1612)
Beatrice Cenci
Italian noblewoman and murderer
Alfonso I d'Este
Duke of Ferrara, Modena and Reggio (1476–1534)
Vannozza dei Cattanei
Italian noble
Francesco II Gonzaga, Marquess of Mantua
ruler of the Italian city of Mantua (1466–1519)
Ippolito de' Medici
Catholic cardinal
Isabella of Naples
Italian duchess of Milan (1470-1524)
Federico II Gonzaga, Duke of Mantua
Marquis and later first Duke of Mantua (1500-1540)
Ercole II d'Este, Duke of Ferrara
Italian noble (1508-1559)
Guglielmo Gonzaga
Duke of Mantua and Montferrat (1538–1587)
Isabella de' Medici
daughter of Cosimo I. de’ Medici and Eleonora of Toledo (1542-1576)
Eleanor de' Medici
Family member of the House of Medici (1567-1611)
Alfonso II d'Este
duke of Ferrara from 1559 to 1597 (1533–1597)
Francesco III Gonzaga, Duke of Mantua
Italian noble
Lucrezia de' Medici
Duchess of Ferrara
Francesco Maria I della Rovere
Italian noble
Virginia de' Medici
Italian noble (1568-1615)
Cesare d'Este, Duke of Modena
Italian noble (1562-1628)
Ippolito d'Este
Catholic cardinal
Francesco IV Gonzaga, Duke of Mantua
Duke of Mantua and Montferrat (1586-1612)
Ippolito II d'Este
Catholic cardinal
Ferrante Gonzaga
Italian nobleman; Governor of the Duchy of Milan
Charles Gonzaga, Duke of Mantua and Montferrat
duke of Mantua and Montferrat (1580–1637)
Bianca Cappello
Italian noble (1548-1587)
Francesco Molin
Doge of Venice (1575-1655)
Guidobaldo II della Rovere
Italian condottiero
Henriette of Cleves
Duchess of Nevers, Countess of Rethel
Antonio Priuli
Doge of Venice (1548-1623)
Francesco Maria II della Rovere
Italian noble, Duke of Urbino
Marcantonio II Colonna
Italian condottiero, politician, patron and admiral
Nicolò Contarini
Doge of Venice (1553-1631)
Gerolama Orsini
16th-century Italian noblewoman
Elisabetta Gonzaga
sister of Francesco II Gonzaga, Marquess of Mantua and by marriage with Guidobaldo da Montefeltro the Duchess of Urbino
Francesco Erizzo
Doge of Venice (1566-1646)
Margherita Aldobrandini
Noblewoman (1588-1646)
Giovanni I Cornaro
Doge of Venice (1551-1629)
Giulia Gonzaga
Italian noblewoman of the Renaissance
Nicolò Donato
Doge of Venice (1539-1618)
Vespasiano I Gonzaga
Italian noble and diplomat (1531-1591)
Clarice de' Medici
Italian noble (1493-1528)
Sancha of Aragon
Princess of Squillace, illegitimate daughter of King Alfonso II of Naples
Anna Juliana Gonzaga
Italian-born Archduchess of Austria and Religious Sister
Eleonora Gonzaga
Duchess of Urbino (1493–1550)
Margherita Gonzaga, Duchess of Ferrara
Italian noble, sponsor of the arts (1564-1618)