16th-century queens regnant

Elizabeth I was Queen of England and Ireland from 17 November 1558 until her death in 1603. She was the last and longest reigning monarch of the House of Tudor. Her eventful reign, and its effect on history and culture, gave name to the Elizabethan era.

Mary, Queen of Scots, also known as Mary Stuart or Mary I of Scotland, was Queen of Scotland from 14 December 1542 until her forced abdication on 24 July 1567.

queen of the Crown of Castile, from 1474 to 1504; first queen of a dynastically-united Spain, from 1479 to 1504 (1451–1504)

Queen of England and Ireland from 1553 to 1558

Queen of England and Ireland in July 1553

Queen of Castile from 1504 and of Aragon from 1516

Queen of Navarre from 1555 to 1572

Queen Regnant of Navarre

kanem-Bornu Empire politician

Tlapalizquixochtzin was an Aztec noblewoman and Queen regnant of the Aztec city of Ecatepec. She was also a consort of Moctezuma II.

Inca queen who co-reigned with Huayna Capac (r. 1487–1525)