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1781 deaths

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Gotthold Ephraim Lessing
German writer, philosopher, publicist, and art critic (1729-1781)
Anne Robert Jacques Turgot
French economist and statesman (1727–1781)
Túpac Amaru II
leader of a large Andean uprising against the Spanish in Peru (1738-1781)
Abram Petrovich Gannibal
African-born Russian general and military engineer (c.1696–1781)
Mariana Victoria of Spain
Infanta of Spain by birth, later regent of Portugal
Josef Mysliveček
Czech composer
Franz Joseph I of Liechtenstein
8th Prince of Liechtenstein 1772–1781 (1726–1781)
Ablai Khan
Kazakh khan
Túpac Katari
indigenous Aymara leader of a major insurrection in colonial-era Upper Peru
Faustina Bordoni
opera singer (1697-1781)
Johannes Ewald
Danish dramatist and poet (1743–1781)
Sadiq Khan Zand
The third Khan of Zand dynasty (1779–1781)
Johann Anton Güldenstädt
Baltic German scientist (1745-1781)
Tobias Furneaux
Royal Navy officer and explorer (1735-1781)
Jean-Frédéric Phélypeaux, Count of Maurepas
French politician (1701-1781)
John Needham
English biologist and Roman Catholic priest (1713-1781)
Johann August Ernesti
German theologian
Giovanni Battista Beccaria
Italian physicist
Micaela Bastidas
martyr of Peruvian independence
Edward Hawke, 1st Baron Hawke
Royal Navy admiral (1705-1781)
Johann Nikolaus Götz
German poet (1721–1781)
Richard Stockton
American lawyer, jurist and legislator (1730–1781)
Balilla
thumb|Balilla monument at Portoria Square in Genoa, Italy
Christophe de Beaumont
Catholic archbishop
José Francisco de Isla
Spanish writer (1703-1781)
James Abercrombie
British Army general (1706-1781)
Friedrich von Wurmb
German botanist (1742-1781)
Ignatius of Laconi
Sardinian saint
Jakob Emanuel Handmann
Swiss painter specialised in portrait painting (1718–1781)
Zenón de Somodevilla, 1st Marqués de la Ensenada
Spanish noble (1702-1781)
William Lewis
English chemist and physician
Tomasa Tito Condemayta
Augustus William, Duke of Brunswick-Bevern
Duke of Brunswick-Bevern
Jean-Baptiste de La Curne de Sainte-Palaye
French academic (1697-1781)
Anna Maria Schwegelin
Alleged German witch
Bernard-Joseph Saurin
French writer
Princess Eleonora of Savoy
member of the House of Savoy (1728-1781)
Théodore Tronchin
Genevan physician
Jean-Baptiste Le Prince
French painter (1734-1781)
Guillaume Le Blond
French mathematician and military historian
George Taylor
representative of Pennsylvania who signed the Declaration of Independence (1716-1781)
George Bogle
Scottish adventurer and diplomat
Francis Dashwood, 11th Baron le Despencer
British politician (1708-1781)
Jan Mikołaj Chodkiewicz
Polish noble (1738–1781)
Francisco Salzillo
Spanish artist
Azad Khan Afghan
Ruler of Asia in 18th century
Bunsan
king of Vientiane
Gregorio Mayans
Historian, linguist and writer
Garret Wesley, 1st Earl of Mornington
Irish politician and aristocrat
Giovanni Ottavio Manciforte Sperelli
Italian cardinal
Johan Henrik Scheffel
Swedish artist (1690-1781)
Mirza Muhammad Rafi Sauda
Urdu poet
Azar Bigdeli
Iranian poet and literary
Richard Challoner
Roman Catholic bishop (1691-1781)
Étienne Aubry
French painter (1745-1781)
Elisabeth Geertruida Wassenbergh
painter from the Northern Netherlands (1729-1781)
Mirza Mazhar Jan-e-Janaan
Indian author
Noël Hallé
French painter and printmaker (1711-1781)
Johann Kies
German astronomer and mathematician
Fernando Rivera y Moncada
Spanish explorer