290s BC establishments

Antioch was a city located in northern Syria at the site of modern Antakya, Turkey. Founded in 300 BC, Antioch became one of the most important cities of the ancient eastern Mediterranean. The capital of the Hellenistic Seleucid Empire, it remained significant under the Roman and Byzantine Empires, and during the Crusades was the centre of the Principality of Antioch.

Foligno (; Southern Umbrian: Fuligno) is an ancient town of Italy in the province of Perugia in east central Umbria, on the Topino river where it leaves the Apennines and enters the wide plain of the Clitunno river system. It is located south-east of Perugia, north-north-west of Trevi and south of Spello.

thumb|300px|Bithynia and Pontus as a province of the Roman Empire, 125 AD Bithynia (; ) is a geographical region of northwestern Asia Minor (in present-day Turkey), adjoining the Sea of Marmara, the Bosporus, and the Black Sea. It borders Mysia to the southwest, Paphlagonia to the northeast along the Black Sea coast, and Phrygia to the southeast towards the interior of Asia Minor.

thumb|350px|Map showing ancient Thessaly. Demetrias is shown to the right on the Pagasaean Gulf. Demetrias () was a Greek city in Magnesia in ancient Thessaly (east central Greece), situated at the head of the Pagasaean Gulf, near the modern city of Volos.

hellenistic kingdom that existed from the 4th century BC to 74 BC