2nd-century BC regents

queen of Ptolemaic Egypt

Empress Regent of the Han dynasty (241–180 BC)

ancient Greek princess and queen

thumb|upright=1.5|Drachm of Agathoclea. The obverse with the queen's portrait and Greek inscription: BAΣIΛIΣΣHΣ ΘEOTPOΠOY AΓAΘOKΛEIAΣ, Basilissēs Theotropou Agathokleias, "Of the Goddess-like queen Agathoclea". Reverse with Strato I standing in armour, and Kharosthi legend: Maharajasa Tratarasa Stratasa Agathukreya, "Of Saviour King Strato and Agathoclea." thumb|upright=1.5|right|Coin of Strato I and Agathoclea. Obverse with the conjugate busts of Strato and Agathoclea, and Greek legend: ΒΑΣΙΛΕΩΣ ΣΩΤΗΡΟΣ ΣΤΡΑΤΩΝΟΣ ΚΑΙ ΑΓΑΘΟΚΛΕΙΑΣ, Basileōs Sōtēros Stratōnos Kai Agathokleias, "Of Saviour King S

Hellenistic queen

Seleucid official

Seleucid general

wife of Ariarathes V of Cappadocia

Amage () (fl. 2nd-century BC) was a Sarmatian queen. According to the writings of Polyaenus, she was the wife of the Sarmatian king Medosacus (Μηδόσακκος). she ruled as regent to a dissolute husband. They were from the coast of the Euxine Sea.

Rinnu (2nd century BC) was a queen consort of the Parthian Empire by marriage to Mithridates I of Parthia (r. 171–132 BC). She was the mother of King Phraates II (r. 132–127 BC) and ruled the Parthian Empire as regent during the minority of her son. She was one of only two women to rule Parthia, the other being queen Musa of Parthia.