5th-century regents

4th-century Roman Empress

Aelia Pulcheria (; ; 19 January 398 or 399 – July 453) was an Eastern Roman empress who advised her brother, the emperor Theodosius II, during his minority and then became wife to emperor Marcian from November 450 to her death in 453.

Emperor of Liu Song from 420 to 422

Prabhavatigupta (died ) was a Gupta princess and Vakataka queen who was the consort of Maharaja Rudrasena II. Following the death of her husband, she effectively ruled the Vakataka Empire as regent from about 390 to 410.

Chinese empress

Liu Song empress

Japanese empress regent (440-484)

Denag (fl. 459), was a Sasanian queen (banbishn). She was the wife of the king (shah) Yazdegerd II (), and functioned as queen regent in Ctesiphon during the civil war between her sons in 457–459.

Northern Wei king