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American musicians with disabilities

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Rachel Bloom
American actress, singer, and producer
John Mellencamp
American singer-songwriter
Victor Wooten
American bass guitarist
Dream
American YouTuber, streamer and singer (born 1999)
Bob Weir
Robert Hall Weir was an American musician and songwriter best known as a founding member of the Grateful Dead. After the group disbanded in 1995, he performed with the Other Ones, later known as the Dead, together with other former members of the Grateful Dead. Weir also founded and played in several other bands during and after his career with the Grateful Dead, including Kingfish, the Bob Weir Band, Bobby and the Midnites, Scaring the Children, RatDog, and Furthur, which he co-led with former Grateful Dead bassist Phil Lesh. In 2015, Weir, along with former Grateful Dead members Mickey Hart and Bill Kreutzmann, joined with singer/guitarist John Mayer, bassist Oteil Burbridge, and keyboardist Jeff Chimenti to form the band Dead & Company.
Paul Wittgenstein
Austrian pianist of Jewish heritage, emigrant from Nazi Austria to USA (1887-1961)
Eddie Money
American musician and singer-songwriter (1949–2019)
Peter Tork
American musician and actor (1942–2019)
Doc Watson
American musician (1923–2012)
Allen Collins
American guitarist (1952–1990)
Gayle
American singer-songwriter
Dan Povenmire
American television director, writer, producer, storyboard artist, and actor
Leon Fleisher
American conductor and pianist (1928–2020)
Fetty Wap
Willie Junior Maxwell II, better known by his stage name Fetty Wap, is an American rapper, singer, and songwriter. He quickly rose to mainstream prominence after his 2014 song "Trap Queen" peaked at number two on the Billboard Hot 100 and led him to sign with 300 Entertainment, an imprint of Atlantic Records. Two of his 2015 singles, "679" and "My Way", peaked within the top ten of the chart; all three—as well as the top 40 single "Again"—preceded his eponymous debut studio album (2015), which peaked atop the Billboard 200. During this time, he became distinctive for his melodic blending of singing and rapping, lighthearted lyrics, "bouncy" production, and exclamation of various catchphrases such as "1738!"
Donny Hathaway
American singer-songwriter and musician (1945-1979)
Carrie Ann Inaba
American television personality, dancer, choreographer, actress, and singer
Leslie West
American singer, guitarist, and songwriter (1945–2020)
Madilyn Bailey
American singer and songwriter
Wynton Kelly
American jazz pianist (1931–1971)
Joyner Lucas
American rapper (born 1988)
Mark Mothersbaugh
American musician and composer
Reneé Rapp
American actress and singer
Johnnie Ray
American singer and pianist (1927–1990)
Blind Willie McTell
Piedmont and ragtime blues singer and guitarist
Vic Chesnutt
singer-songwriter from Athens, Georgia (1964–2009)
Big Walter Horton
American blues harmonica player (1921–1981)
Ethel Cain
American singer-songwriter, born 1998
Francis Hopkinson
American politician, judge, and author 1737-1791
Doc Pomus
American recording artist; blues singer, lyricist, songwriter (1925–1991)
Dallon Weekes
American musician
Blind Blake
American blues singer and guitarist (1896–1934)
Brittany Howard
American singer
Taylor York
American guitarist
Jim Byrnes
American musician and actor
Diane Schuur
American jazz musician
Sylvain Sylvain
American guitarist (1951–2021)
Dorian Electra
American singer-songwriter
Billy Joe Shaver
American country singer (1939–2020)
Chrisette Michele
American singer
Nessa Barrett
American singer
Muni Long
American singer
Stephen Malkmus
American musician
Snow Tha Product
American rapper and singer
Dave Liebman
American jazz composer, saxophonist and flautist
Fredo Santana
American rapper (1990-2018)
Wesley Willis
American musician and artist (1963–2003)
Mary Lambert
American singer-songwriter and poet
Alexei Sultanov
Uzbekistani musician (1969–2005)
Kiana Ledé
American singer and actress
Bushwick Bill
Jamaican rapper (1966–2019)
Gary Graffman
American musician (1928–2025)
Connee Boswell
American musician (1907–1976)
Tony Jackson
American pianist, singer, and composer (1876–1921)
Austin Carlile
American singer
Will Wood
American musician
Marcus Roberts
American musician
Residente
René Pérez Joglar (; born February 23, 1978), known professionally as Residente (often stylized as Resīdɛntə), is a Puerto Rican rapper. He is best known as one of the founders of the alternative rap band Calle 13. Residente released five albums with Calle 13 before announcing his solo career in 2015. Residente released his debut solo album in 2017. He has won four Grammy Awards and 29 Latin Grammy Awards—more than any other Latin artist. Residente has also delved into producing documentaries including Sin Mapa (2009) and Residente (2017) and has directed some of his own music videos.
George Watsky
American rapper
Wingy Manone
American musician (1900-1982)
Michael Ponti
German pianist (1937–2022)