Category
page 1Aporphine alkaloids
glaucine
Glaucine (also known as 1,2,9,10-tetramethoxyaporphine, bromcholitin, glauvent, tusidil, and tussiglaucin) is an aporphine alkaloid found in several different plant species in the family Papaveraceae, such as Glaucium flavum, Glaucium oxylobum, and Corydalis yanhusuo, and in other plants such as Croton lechleri in the family Euphorbiaceae.
(S)-(+)-bulbocapnine
Bulbocapnine is an alkaloid found in Corydalis (notably the European species C. cava) and Dicentra, genera of the plant family Fumariaceae which have caused (notably the American species Corydalis caseana) the fatal poisoning of sheep and cattle. It has been shown to act as an acetylcholinesterase inhibitor, and inhibits biosynthesis of dopamine via inhibition of the enzyme tyrosine hydroxylase. Like apomorphine, it is reported to be an inhibitor of amyloid beta protein (Aβ) fiber formation, whose presence is a hallmark of Alzheimer's disease (AD). Bulbocapnine is thus a potential therapeutic
nantenine
Nantenine is an alkaloid found in the plant Nandina domestica as well as some Corydalis species. It is an antagonist of both the α1-adrenergic receptor and the serotonin 5-HT2A receptor, and blocks both the behavioral and physiological effects of MDMA in animals.
boldine
Boldine is an alkaloid of the aporphine class that is characteristic of the boldo tree Peumus boldus Molina. It is the most abundant alkaloid found in boldo bark, although it is not present in the leaves. Boldine is also found in Lindera aggregata.
aporphine
Aporphine is an alkaloid with the chemical formula . It is the core chemical substructure of the aporphine alkaloids, a subclass of quinoline alkaloids. It can exist in either of two enantiomeric forms, (R)-aporphine and (S)-aporphine.
(-)-annonaine
Anonaine is a bioactive noraporphine, present in members of the plant families Magnoliaceae and Annonaceae It is named after the plant it was first extracted from, Annona reticulata, which is commonly known as Anona.
Pukateine
Pukateine is an alkaloid found in the bark of the New Zealand tree Laurelia novae-zelandiae ("Pukatea"), as well as some South American plants. An extract from pukatea is used in traditional Māori herbal medicine as an analgesic.
magnoflorine
(S)-Magnoflorine is a quaternary benzylisoquinoline alkaloid (BIA) of the aporphine structural subgroup which has been isolated from various species of the family Menispermaceae, such as Pachygone ovata, Sinomenium acutum, and Cissampelos pareira.
nuciferine
Nuciferine is an alkaloid found within the plants Nymphaea caerulea and Nelumbo nucifera.
aporphine alkaloids
class of compounds
Asimilobine
Asimilobine is an inhibitor of dopamine biosynthesis, and a serotonergic receptor antagonist.
xylopine
Xylopine is an antimicrobial benzylisoquinoline alkaloid.
domesticine
Domesticine is an α1D-adrenergic receptor antagonist. The compound belongs to the group of aporphine alkaloids.
hernandaline
Hernandaline is one of a class of quinoline alkaloids with chemical formula C29H31NO7 C29H31NO7 . This compound has been isolated from the stem bark of Hernandia ovigera (Hernandiaceae). Studies have established than hernandaline has hypotensive activity. Its optical rotation is [\alpha]_D^{20} = +36.5°.