Autoinflammatory syndromes

rare immune-mediated small-vessel systemic vasculitis in humans

Human disease

multisystem disease

fevers of unknown etiology recurring over months or years

PFAPA (Periodic fever - aphthous stomatitis- pharyngitis - adenopathy) syndrome is an auto inflammatory syndrome characterized by recurrent febrile episodes associated with aphthous stomatitis, pharyngitis and cervical adenitis

Human disease

autosomal dominant disease characterized by familial granulomatous arthritis, uveitis and skin granulomas. It has material basis in mutations in the NOD2/CARD15 genes

Pyogenic arthritis-pyoderma gangrenosum-acne syndrome is a rare pleiotropic autoinflammatory disorder of childhood, primarily affecting the joints and skin

Systemic inflammatory disorder, and a subtype of juvenile idiopathic arthritis, associated with fever, rash, and arthritis.

human disease

group of rare autosomal dominant diseases

human disease

Majeed syndrome is a rare genetic multisystemic disorder characterized by the triad of chronic recurrent multifocal osteomyelitis, congenital dyserythropoietic anemia, and variable transient inflammatory dermatosis

Human disease