Chromoanagenesis

350px|thumb| alt=massive gene rearrangement event leading as a result of chromothripsis leading to cancer|Chromothripsis: Single catastrophic event in a cell's history Chromothripsis is a mutational process by which up to thousands of clustered chromosomal rearrangements occur in a single event in localised and confined genomic regions in one or a few chromosomes, and is known to be involved in both cancer and congenital diseases. It occurs through one massive genomic rearrangement during a single catastrophic event in the cell's history. It is believed that for the cell to be able to withstan