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Comics set in the United States

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Calvin and Hobbes
comic strip by Bill Watterson
Sin City
comic books series by Frank Miller
XIII
Belgian graphic novel series
Steel Ball Run
Seventh part of JoJo's Bizarre Adventure
Buster Brown
comic strip character created in 1902 by Richard Felton Outcault
Life in Hell
comic strip
Buddy Longway
comic book
Duckman
Duckman: Private Dick/Family Man, commonly known simply as Duckman, is an American adult animated sitcom created and developed by Everett Peck, based on the characters he created in his 1990 one-shot comic book published by Dark Horse Comics. Duckman aired on the USA Network from March 5, 1994, through September 6, 1997, for 4 seasons and 70 episodes. It follows the surreal life and misadventures of Eric Tiberius Duckman (voiced by Jason Alexander), a private detective who lives with his family. The series is known for a unique blend of satire, dark humor, noir, and surrealism.
Il Grande Blek
Italian western comic book
The Boondocks
American comic strip (1996–2006)
Bruno Brazil
comic book series
Pogo
American comic strip
The Master of the Mississippi
chapter 2 of The Life and Times of Scrooge McDuck
Gasoline Alley
American comic strip created by Frank King
Transformers
comics
Redeye
comic strip
FoxTrot
FoxTrot is an American comic strip written and illustrated by Bill Amend. The strip launched on April 10, 1988, and it originally ran seven days a week. From December 31, 2006 onwards, FoxTrot has only appeared on Sundays.
The Empire-Builder from Calisota
chapter 11 of the Life and Times of Scrooge McDuck
The Buckaroo of the Badlands
chapter 3 of The Life and Times of Scrooge McDuck
Sammy
Belgian comics series
Piranha Club
comic strip
Willie Lumpkin
fictional character in Marvel Comics
Goodman Beaver
fictional character
Popol out West
a comic by the Belgian cartoonist Hergé
The Transformers
comic book series published by Marvel Comics
The Sharpie of the Culebra Cut
chapter 10B of The Life and Times of Scrooge McDuck
U.S. Acres
comic strip by Jim Davis