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DC Comics female supervillains

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Catwoman
Catwoman is a character appearing in American comic books published by DC Comics. Created by Bill Finger and Bob Kane, she debuted as "the Cat" in Batman #1 (spring 1940). She has become one of the superhero Batman's most prominent enemies, belonging to the collective of adversaries that make up his rogues gallery, as well as Batman's best known and most enduring love interest, with many stories depicting their complex love–hate relationship. Since 1993, Catwoman has had her own ongoing series, Catwoman.
Harley Quinn
fictional character in DC Comics
Poison Ivy
fictional character throughout the DC Universe
Clayface
Clayface is an alias used by several characters appearing in American comic books published by DC Comics. Most incarnations of the character possess clay-like bodies and shapeshifting abilities, and all of them are adversaries of the superhero Batman. In 2009, Clayface was ranked as IGNs 73rd-greatest comic book villain of all time.
Cheetah
supervillain appearing in DC Comics publications and related media
Talia al Ghul
fictional villain in Batman comics series
Ventriloquist
enemy of Batman in the DC Comics Universe
Amanda Waller
DC Comics character
Enchantress
supervillain appearing in DC Comics publications and related media
Huntress
name of Multiple DC Comics Superheroes
Killer Frost
fictional character from DC Comics
Cassandra Cain
DC Comics superhero
Firefly
fictional character in DC Comics
Parasite
fictional character from the Superman comics
Giganta
Giganta is a fictional character appearing American comic books published by DC Comics, commonly as a recurring adversary of the superhero Wonder Woman, and an occasional foil of the superhero the Atom. She debuted as a brutish strongwoman in 1944's Wonder Woman #9, written by Wonder Woman creator William Moulton Marston and illustrated by Harry G. Peter, and went on to become one of Wonder Woman's most recognizable and persistent foes, appearing during every major era of the hero's comic book adventures, and adapted frequently for television and animation.
Superwoman
Superwoman is the name of several fictional characters in DC Comics. Most of them are, like Supergirl, women with powers similar to those of Superman, such as flight, invulnerability, and enhanced strength.
Terra
DC Comics character
Evey Hammond
fictional character from V for Vendetta
Circe
fictional character in DC Comics
Lena Luthor
fictional character from DC Comics
Star Sapphire
several comic book characters
Blackfire
DC Comics villain, sister of Starfire
Lady Shiva
fictional character
Golden Glider
Fictional character by DC Comics
Isis
DC Comics superhero
Rose Wilson
DC Comics supervillain
Doctor Poison
DC Comics Villain
Jinx
DC Comics character
Duela Dent
one of several fictional characters using the identity Harlequin
Granny Goodness
DC Comics character
Faora
Faora is a supervillain appearing in American comic books published by DC Comics, commonly in association with Superman. The character was created by Cary Bates and Curt Swan, and first appeared in Action Comics #471 (May 1977). Most commonly, Faora is an ally and sometimes the wife or lover of Superman's Kryptonian nemesis General Zod.
Silver Banshee
fictional character
Punchline
DC Comics character
Female Furie
group of fictional women from DC Comics
Cheshire
comic book character
Madame Rouge
DC Comics character
Ursa
fictional character of the DC Universe
Plastique
range from supporting characters, heroes and villains that appear infrequently, to characters that only take part in a single story
Copperhead
DC Comics supervillain
Eve Teschmacher
DC Comics character
Tigress
comic book supervillains
Sofia Falcone
DC Comics character
Carol Ferris
fictional character in DC Comics
Livewire
DC Comics character
Mercy Graves
character from "Superman: The Animated Series" and later media
Mazikeen
Mazikeen is a character who appears in American comic books published by DC Comics. She is one of the Lilim, a child of Lilith. She first appeared in The Sandman (vol. 2) #22 (December 1990), and was created by Neil Gaiman and Kelley Jones. Her name comes from the term "Mazzikin", invisible demons which can create minor annoyances or greater dangers according to Jewish mythology.
Roulette
DC Comics villainess
Villainy Inc.
Fictional group of supervillains who battle Wonder Woman
Maxima
character from the DC Comics Superman titles
Cupid
fictional comic book character, a villainess of Green Arrow and Black Canary
Knockout
fictional character, a supervillainess in the DC Comics universe
Fury
any one of three DC Comics superheroes
Paula Brooks
DC Comics character
Harley Quinn
DC Extended Universe character