Category
page 1Drug development
COVID-19 drug development
preventative and therapeutic medications for COVID-19 infection
Lipinski's rule of five
rule of thumb that a compound is likely orally active if it violates at most one of: ≤5 hydrogen bond donors; ≤10 hydrogen bond acceptors; molecular mass of ≤500 Da; octanol-water partition coefficient of ≤5
drug development
process of bringing a new pharmaceutical drug to the market once a lead compound has been identified
contract research organization
type of healthcare company
new chemical entity
according to the U.S. Food and Drug Administration, a drug that contains no active moiety that has been approved by the FDA in any other application submitted under section 505(b) of the Federal Food, Drug, and Cosmetic Act
drug repositioning
subfield of pharmacology
pre-clinical development
preclinical testing of drugs in experimental animals or in vitro for their biological and toxic effects and potential clinical applications
approved drug
pharmaceutical product that successfully completed drug approval process