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Genetically engineered characters in video games

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Shadow the Hedgehog
fictional character from the Sonic franchise
Mewtwo
Mewtwo (; Japanese: , Hepburn: ) is a Pokémon species in Nintendo and Game Freak's Pokémon media franchise. It was first introduced in the video games Pokémon Red and Blue, and later appeared in subsequent sequels and spin-off titles, such as Pokkén Tournament and Detective Pikachu. In the video games, the player can fight and capture Mewtwo in order to subsequently pit it against other Pokémon. The player can first learn of Mewtwo late in Pokémon Red and Blue by reading research documents left in a ruined laboratory on Cinnabar Island where Mewtwo has escaped. Mewtwo is regarded as one of the
Agent 47
fictional assassin from the Hitman franchise
Solid Snake
fictional character from the Metal Gear series
Crash Bandicoot
fictional video game character
Albert Wesker
fictional character from Resident Evil
Sephiroth
fictional character from Final Fantasy VII
Mileena
Mileena ( ) is a character in the Mortal Kombat fighting game franchise by Midway Games and NetherRealm Studios. Introduced in Mortal Kombat II (1993), Mileena was initially depicted as a clone of the Edenian princess Kitana, created by Shang Tsung with the blood of the fictional Tarkatan species. In the reboot entry Mortal Kombat (2011), Mileena's background as a clone of Kitana remains the same. Mortal Kombat X (2015) depicts Mileena's attempts to regain the throne as the empress of Outworld, following her removal by Kotal Kahn.
Cloud Strife
protagonist of Final Fantasy VII
Nemesis
fictional character in Capcom's Resident Evil franchise
Liquid Snake
fictional character from the Metal Gear series
Zack Fair
character in Final Fantasy
Vincent Valentine
Final Fantasy VII Character
Aya Brea
fictional character from Parasite Eve
Zidane Tribal
character from Final Fantasy IX
K'
is a character from The King of Fighters fighting game series developed by SNK. He debuted as the leader of the Hero Team in ''The King of Fighters '99'', released in 1999. He often stars as the reluctant hero. K' is a young man who lost all his memories when the NESTS syndicate captured him and injected the DNA of Kyo Kusanagi to replicate his pyrokinetic abilities. While rebelling against organization, K' forms multiple bonds with other NESTS agents. Aside from the main series, K' also appears in several other media series, such as spin-offs and crossover video games, as well as printed adap
Kefka Palazzo
fictional character from Final Fantasy VI
Big Daddy
fictional character from BioShock