German companies established in 2000

thumb|Headquarters of CureVac in Tübingen CureVac is a biopharmaceutical company based in Tübingen, Germany that develops therapies based on messenger RNA (mRNA). With approximately 375 employees in 2018, it was founded in 2000 by Ingmar Hoerr, Steve Pascolo, Florian von der Mulbe, Günther Jung, and Hans-Georg Rammensee.

T-Systems International GmbH, trading as T-Systems, is an internationally operating service provider for information technologies and digital transformation. The company is part of Deutsche Telekom and is headquartered in Frankfurt am Main.

www.handy-games.com GmbH (trade name: HandyGames) is a German video game developer and publisher based in Giebelstadt. In July 2018, the company was acquired by THQ Nordic.

German design hotel group

German musical software company

Astragon Entertainment GmbH is a German video game publisher based in Düsseldorf, Germany. Originally a subsidiary of the German video game distributor Astragon Sales & Services GmbH (formerly Rondomedia Marketing & Vertriebs GmbH), the company became known for being the original worldwide publisher of the Farming Simulator series and continues to publish it across the world.