Isoxazolidinones

Cycloserine, sold under the brand name Seromycin, is an antibiotic, used to treat tuberculosis. Specifically it is used, along with other antituberculosis medications, for active drug resistant tuberculosis. It is given by mouth.

Terizidone is a drug used in the treatment of tuberculosis. Terizidone is mainly used in multi-drug-resistant tuberculosis (MDR-TB) in conjunction with other second-line drugs. It is a derivative of cycloserine with bacteriostatic activity.

Clomazone is an agricultural herbicide, and has been the active ingredient of products named Command and Commence. The molecule consists of a 2-chlorobenzyl group bound to a nitrogen-oxygen heterocycle called a isoxazolidinone. It is a white solid.

The oxazolidones and isoxazolidones are a set of six isomeric five-membered heterocyclic compounds consisting of a carbonyl group, an oxygen atom, a nitrogen atom with a hydrogen atom attached, and two methylene groups. The chemicals differ in the relative position of these groups around the ring, which results in different functional group combinations.

Gaboxadol, also known as 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol (THIP) and by its former developmental code names Lu-2-030, MK-0928, and OV101, is a GABAA receptor agonist related to muscimol which was investigated for the treatment of insomnia and other conditions like Angelman syndrome but was never marketed. At lower doses, the drug has sedative and hypnotic effects, and at higher doses, it produces hallucinogenic effects. It is taken orally.