Pennsylvanian genus first appearances

Edaphosaurus (, meaning "pavement lizard" for dense clusters of its teeth) is a genus of extinct edaphosaurid synapsids that lived in what is now North America and Europe around 303.4 to 272.5 million years ago, during the Late Carboniferous to Early Permian. The American paleontologist Edward Drinker Cope first described Edaphosaurus in 1882, naming it for the "dental pavement" on both the upper and lower jaws, from the Greek ' ("ground"; also "pavement") and (') ("lizard").

Sphenacodon (meaning "wedge point tooth") is an extinct genus of synapsid that lived from about 300 to about 280 million years ago (Ma) during the Late Carboniferous and Early Permian periods. Like the closely related Dimetrodon, Sphenacodon was a carnivorous member of the Eupelycosauria family Sphenacodontidae. However, Sphenacodon had a low crest along its back, formed from blade-like bones on its vertebrae (neural spines) instead of the tall dorsal sail found in Dimetrodon. Fossils of Sphenacodon are known from New Mexico and the Utah–Arizona border region in North America.

Hylonomus (; from Greek , meaning , and , meaning ) is an extinct genus of early (possibly stem group) amniote that lived during the Bashkirian stage of the Late Carboniferous. The genus contains a single species, Hylonomus lyelli.

Ophiacodon (meaning "snake tooth") is an extinct genus of synapsid belonging to the family Ophiacodontidae that lived from the Late Carboniferous to the Early Permian in North America and Europe. The genus was named along with its type species O. mirus by paleontologist Othniel Charles Marsh in 1878 and currently includes five other species. As an ophiacodontid, Ophiacodon is one of the most basal synapsids and is close to the evolutionary line leading to mammals.

Limnoscelis (/limˈnäsələ̇s/, meaning "marsh footed") is an extinct genus of large diadectomorph tetrapods from the Late Carboniferous to early Permian of western North America. It includes two species: the type species Limnoscelis paludis from New Mexico, and Limnoscelis dynatis from Colorado, both of which are thought to have lived concurrently. No specimens of Limnoscelis are known from outside of North America. Limnoscelis was carnivorous, and likely semiaquatic, though it may have spent a significant portion of its life on land. Limnoscelis had a combination of derived amphibian and primit

Amblypterus (from , 'blunt' and 'wing' or 'fin') is an extinct genus of freshwater ray-finned fish that lived during the Gzhelian (upper Carboniferous) and Cisuralian (lower Permian) epoch in what is now Europe (Czech Republic, France, Germany, Switzerland) and possibly India and Argentina. Potential indeterminate records stretch as far back as the early Carboniferous.

Elonichthys is an extinct genus of prehistoric freshwater ray-finned fish known from the late Paleozoic. The genus sensu stricto contains three species known from the latest Carboniferous to the earliest Permian of freshwater ecosystems of Europe, but as a former wastebasket taxon, it contains many more dubiously-classified species from the Carboniferous and Permian of Europe, Greenland, South Africa, and North America.