Regional capitals in Guinea

Conakry ( , ; ; ; ) is the capital and largest city of Guinea. A port city, it serves as the economic, financial and cultural centre of Guinea. Its population as of the 2025 Guinea census was 3,407,327, or around one-sixth of the country's population.

Nzérékoré (N’ko: , Adlam: ; also spelled '''N'Zérékoré''') is the third largest city in Guinea by population after the capital, Conakry and Kankan, and the largest city in the Guinée forestière region of southeastern Guinea. The city is the capital of Nzérékoré Prefecture. Nzérékoré is a commercial and economic center and lies approximately southeast of Conakry.

Kindia (N’ko: ߞߌ߲ߘߌߦߊ߫) is the fourth largest city in Guinea, located about northeast of the nation's capital, Conakry. Its estimated population in 2008 was 181,126. Kindia serves as the capital and largest city of Kindia Prefecture and Kindia Region. It also functions as a sub-prefecture of Guinea.

Mamou (Pular: 𞤃𞤢𞥄𞤥𞤵𞤲) is a city and sub-prefecture in a valley of the Fouta Djallon area of Guinea. The population is 376,269 (2018 est).

Faranah (N’ko: ߝߙߊߣߊ߫߫) is a town and sub-prefecture in central Guinea, lying by the River Niger. As of 2014 it had a population of 78,108 people. The town is mainly inhabited by the Malinke people.