RNA

thumb|2'-O-methyl-adenosine, a modified adenosine. '''2'-O-methylation (2'-O-Me''') is a nucleotide epitranscriptomics modification commonly found in ribosomal RNA (rRNA), transfer RNA (tRNA), and small nuclear RNA (snRNA). This modification is created through post-transcriptional modification of the RNA. This modification can be performed via ribonucleoprotein (snoRNP) with C/D box small nucleolar RNA (snoRNA) used as a guide RNA where a methyl group is added to the 2' hydroxyl of the ribose moiety of any nucleotide (Nm) producing a methoxy group. It can also be performed through other enzyme

type of noncoding RNA found in cells

Control of gene expression at the RNA level, between transcription and translation

Catalyzes reversible cleavage and ligation within an RNA molecule

type of RNA

concept in genetics

thumb|right|250 px|Structure of a GNRA tetraloop from a group I self-splicing intron. Tetraloops are a type of four-base hairpin loop motifs in RNA secondary structure that cap many double helices. There are many variants of the tetraloop. The published ones include ANYA, CUYG, GNRA, UNAC and UNCG.

Biological molecule

Biological gene-regulation phenomenon

a eukaryotic RNA transcript

type of RNA

class of enzymes

class of medications

hypothesis that some organisms store memory in RNA outside the nervous system

class of chemical compounds

Eterna is a browser-based "game with a purpose", developed by scientists at Carnegie Mellon University and Stanford University, that engages users to solve puzzles related to the folding of RNA molecules. The project is supported by the Bill and Melinda Gates Foundation, Stanford University, and the National Institutes of Health. Prior funders include the National Science Foundation.

molecular biology method used to detect specific RNA sequences

An alarmone is an intracellular signal molecule that is produced in bacteria, chloroplasts, and a slim minority of archaea reacting to harsh environmental factors. They regulate the gene expression at transcription level. Alarmones are produced in high concentrations when harsh environmental factors occur in bacteria and plants, such as lack of amino acids, to produce proteins. Stringent factors take uncharged tRNA and convert it to an alarmone. Guanosine-5'-triphosphate (GTP) is then converted to 5´-diphosphate 3´-diphosphate guanosine (ppGpp), the archetypical alarmone. ppGpp will bind to RN

Rfam is a database containing information about non-coding RNA (ncRNA) families and other structured RNA elements. It is an annotated, open access database originally developed at the Wellcome Trust Sanger Institute in collaboration with Janelia Farm, and currently hosted at the European Bioinformatics Institute. Rfam is designed to be similar to the Pfam database for annotating protein families.