Smallpox vaccines

English physician, scientist and pioneer of vaccination (1749–1823)

noblewoman; writer and poet from England, editor (1689-1762)

Cowpox is an infectious disease caused by Cowpox virus (CPXV). It presents with large blisters in the skin, a fever and swollen glands, historically typically following contact with an infected cow, though in the last several decades more often (though overall rarely) from infected cats. The hands and face are most frequently affected and the spots are generally very painful.

Inoculation is the act of implanting a pathogen or other microbe or virus into a person or other organism. It is a method of artificially inducing immunity against various infectious diseases. The term "inoculation" is also used more generally to refer to intentionally depositing microbes into any growth medium, as into a Petri dish used to culture the microbe, or into food ingredients for making cultured foods such as yoghurt and fermented beverages such as beer and wine. This article is primarily about the use of inoculation for producing immunity against infection. Inoculation has been used

first successful vaccine to be developed

thumb|upright=1.8|"Queens" of Mysore: left, [[Krishnaraja Wadiyar III's first wife, Devajammani has a discoloration around the mouth, thought to be due to the blowing of variolation dust in the nose ("nasal insufflation"). Right, his second wife shows the discrete mark left by vaccination under her saree. Thomas Hickey, 1805.]] Variolation was the method of inoculation first used to immunize individuals against smallpox (Variola) with material taken from a patient or a recently variolated individual, in the hope that a mild, but protective, infection would result. Only 1–2% of those variolated

social event held in an attempt to inoculate children through exposure to infectious disease

1904 week of civil disorder in Rio de Janeiro, Brazil

epidemic

thumb|Smallpox vaccine needle ACAM2000 is a smallpox vaccine and an mpox vaccine manufactured by Emergent Biosolutions. It provides protection against smallpox for people determined to be at high risk for smallpox infection. ACAM2000 is a live replicating vaccinia virus vaccine.

American physician

British farmer and doctor

1905 United States Supreme Court case