Software that uses PyGTK

BitTorrent client

PyGTK is a set of Python wrappers for the GTK graphical user interface library. PyGTK is free software and licensed under the LGPL. It is analogous to PyQt/PySide and wxPython, the Python wrappers for Qt and wxWidgets, respectively. Its original author is GNOME developer James Henstridge. There are six people in the core development team, with various other people who have submitted patches and bug reports. PyGTK has been selected as the environment of choice for applications running on One Laptop Per Child systems.

Gajim is an instant messaging client for the XMPP protocol which uses the GTK toolkit. The name Gajim is a recursive acronym for "Gajim's a jabber instant messenger". Gajim runs on Linux, BSD, macOS, and Microsoft Windows. Released under the GPL-3.0-only license, Gajim is free software. A 2009 round-up of similar software on Tom's Hardware found version 0.12.1 "the lightest and fastest jabber IM client".

BleachBit is a free and open-source disk space cleaner, privacy manager, and computer system optimizer. The BleachBit source code is licensed under the GNU General Public License version 3.

Wicd, which stands for Wireless Interface Connection Daemon, is an open-source software utility to manage both wireless and wired networks for Linux. The project started in late 2006 with the creation of Connection Manager, which eventually became Wicd. Wicd aims to provide a simple interface to connect to networks with a wide variety of settings.

PyChess is a free software chess client developed for GNU. It allows users to play offline or online via the Free Internet Chess Server (FICS). PyChess also incorporates a built-in chess engine, which in contrast to most other chess AIs is written in the Python language and focuses more on fun of play than raw strength. For more advanced users, PyChess allows for virtually any other external chess engine to be used with it.

user interface dock for Linux

Virtaal () is a computer-assisted translation tool written in the Python programming language. It is free software developed and maintained by Translate.org.za.