Category
page 1Statistical genetics
population genetics
subfield of genetics that deals with genetic differences of populations, part of evolutionary biology
Hardy–Weinberg principle
principle that allele and genotype frequencies in a population will remain constant over generations in the absence of other evolutionary influences
quantitative trait locus
DNA locus associated with variation in a quantitative trait
Luria-Delbrück experiment
experiment showing that in bacteria, genetic mutations arise in the absence of selection, rather than being a response to selection.
coalescent theory
model for tracing the history of genetic variation
Polygenic score
Score that is the effect of many genetic variants on an individual's phenotype, calculated as a weighted sum of trait-associated alleles
Idealised population
imputation
genetics term; statistical inference of unobserved genotypes
genetic correlation
the proportion of variance that two traits share due to genetic causes, the correlation between the genetic influences on a trait and the genetic influences on a different trait estimating the degree of pleiotropy or causal overlap
Substitution model
model of changes in a sequence over evolutionary time