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Video games about diseases

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Far Cry 2
2008 video game
Batman: Arkham City
2011 video game
Dishonored
Dishonored is a 2012 action-adventure game developed by Arkane Studios and published by Bethesda Softworks. Set in the fictional, plague-ridden industrial city of Dunwall, Dishonored follows the story of Corvo Attano, bodyguard to the Empress of the Isles. He is framed for her murder and forced to become an assassin, seeking revenge on those who conspired against him. Corvo is aided in his quest by the Loyalistsa resistance group fighting to reclaim Dunwall, and the Outsidera powerful being who imbues Corvo with magical abilities. Several actors, including Susan Sarandon, Brad Dourif, Carrie F
Bloodborne
is a 2015 action role-playing game developed by FromSoftware and published by Sony Computer Entertainment for the PlayStation 4. The game follows a Hunter through the decrepit Gothic, Victorian-era inspired city of Yharnam, whose inhabitants are afflicted with a blood-borne disease which transforms the residents into horrific beasts. Attempting to find the source of the plague, the player's character unravels the city's mysteries while fighting beasts and cosmic beings.
Avowed
Avowed is an action role-playing game developed by Obsidian Entertainment and published by Xbox Game Studios. The game is set in the world of Eora, the same universe as Pillars of Eternity. It was released for Windows and Xbox Series X/S on February 18, 2025, and for PlayStation 5 on February 17, 2026. The game received generally positive reviews from critics, but failed to meet the sales expectations of Xbox Game Studios.
Heretic II
1998 video game
Q109328658
2025 action role-playing video game developed by Leenzee Games
Captain Novolin
1992 video game