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YouTubers with disabilities

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Technoblade
Alexander (June 1, 1999 – June 2022), known online as Technoblade ( ), was an American YouTuber known for his Minecraft videos, livestreams, and involvement in the Dream SMP. Technoblade registered his main channel on YouTube in 2013. His videos consisted primarily of Minecraft gameplay, particularly on the minigame server Hypixel. After rising to popularity in 2019 for his performances in player versus player (PvP) events, Technoblade was invited to the Dream SMP Minecraft server in 2020, further increasing his following.
Jacksepticeye
Seán William "Jack" McLoughlin ( ; born 7 February 1990), better known by his online pseudonym jacksepticeye, is an Irish YouTuber whose videos focus on gaming, comedy, and vlogging.
Tay Zonday
American YouTube personality
John Hinckley
attempted assassin of Ronald Reagan (born 1955)
Dream
American YouTuber, streamer and singer (born 1999)
Ryan Higa
American Internet personality and actor
Dan Povenmire
American television director, writer, producer, storyboard artist, and actor
Like Nastya
Russian-American YouTuber and actor
Andrea Botez
Canadian-American chess player and Twitch streamer
TomSka
Thomas James Ridgewell (born 27 June 1990), known online as TomSka, is a British YouTuber, filmmaker, vlogger, video essayist, and actor. He is known for writing, directing, producing, and starring in his live-action sketch comedy YouTube videos, video essays, and animated web series such as Asdfmovie ( ), Crash Zoom, and Eddsworld where he both provided the voice and inspired the character of Tom and served as showrunner from 2012 to 2016. , his YouTube channel has over 7.46 million subscribers, and his videos have garnered over 2.1 billion views.
Reckful
Byron Daniel Bernstein (May 8, 1989 – July 2, 2020), better known as Reckful, was an American-Israeli Twitch streamer and professional esports player. He was best known in the gaming community for his achievements in World of Warcraft and ''Asheron's Call''.
FouseyTube
Yousef Saleh Erakat ( ; , ; born January 22, 1990), also known as FouseyTube or Fousey ( ), is an American YouTuber, online streamer, actor, and musician. His YouTube channels include FouseyTUBE (later renamed Crashout YSE), and the reality vlog-channel DOSEofFOUSEY. As a YouTuber, he produces prank videos, parodies, vlogs, comedy sketches and interviews. He is the recipient of two Streamy Awards. As an actor, he starred in Tyler Perry's comedy horror film Boo! A Madea Halloween (2016) and its 2017 sequel. In January 2025, he released his debut album, G7: The Death of Fousey, which earned nega
Vaush
Ian Anthony Kochinski (born February 14, 1994), better known as Vaush ( ), is an American left-wing YouTuber and former Twitch streamer. Kochinski started his online career as a member of streamer Destiny's community, before creating his Twitch channel and YouTube account in 2019. His content consists of commentary on various news and media topics, men's fashion, video games, and urbanist policies. Debates and discussions with various political figures have been a large part of his channel. Noted for his confrontational style, use of memes, and mimicry from right-wing YouTubers, he is regarded
Jaiden Animations
American YouTuber and animator
Mel Baggs
American blogger (1980–2020)
Ironmouse
Ironmouse (born January 11) is a Puerto Rican VTuber, singer, and Twitch streamer. Active since 2017, she was a founding member of the U.S.-based VTuber agency VShojo and was part of the organization from November 2020 until her departure in July 2025.
Sweet Anita
British Twitch streamer and YouTuber
Chloé Hayden
Australian actress, social media personality, disability rights activist, podcast host and author
Gabbie Hanna
American singer-songwriter
Amane Kanata
Japanese virtual YouTuber
Drew Lynch
American stand-up comedian (born 1991)
Molly Burke
Canadian motivational speaker
Jessica McCabe
American actress