Also known as 1,4-Dimethyl-2,3-benzphenanthrene, 9,10-Dimethylbenz(a)anthracene, 7,12-Dimethylbenzanthrancene, 7,12-Dimethyl-1:2-benz(a)anthracene, 7,12-Dimethyl-1,2-benzanthracene, 7,12-DMBA, 6,7-Dimethyl-1,2-benzanthracene
'7,12-Dimethylbenz[a]anthracene (DMBA') is an immunosuppressor and a powerful organ-specific laboratory carcinogen. DMBA is widely used in many research laboratories studying cancer. DMBA serves as a tumor initiator. Tumor promotion can be induced with treatments of 12-O-tetradecanoylphorbol-13-acetate (TPA) in some models of two-stage carcinogenesis. This allows for a greatly accelerated rate of tumor growth, making many cancer studies possible.
via PubMed
'7,12-Dimethylbenz[a]anthracene (DMBA') is an immunosuppressor and a powerful organ-specific laboratory carcinogen. DMBA is widely used in many research laboratories studying cancer. DMBA serves as a tumor initiator. Tumor promotion can be induced with treatments of 12-O-tetradecanoylphorbol-13-acetate (TPA) in some models of two-stage carcinogenesis. This allows for a greatly accelerated rate of tumor growth, making many cancer studies possible.
==References==
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