ketone body biosynthetic process
Also known as GO:0046951, ketone body synthesis, ketone body anabolism, ketone body formation, ketone body biosynthesis, Ketogenesis, ketogenesis
thumb|upright=1.2|class=skin-invert-image|Ketogenesis pathway. The three ketone bodies (acetoacetate, acetone, and beta-hydroxy-butyrate) are marked within orange boxes
Article
7 sectionsContents
- Production
- Ketone bodies
- Regulation
- Pathology
- See also
- References
- External links
thumb|upright=1.2|class=skin-invert-image|Ketogenesis pathway. The three ketone bodies (acetoacetate, acetone, and beta-hydroxy-butyrate) are marked within orange boxes
Ketogenesis is the biochemical process through which organisms produce ketone bodies by breaking down fatty acids and ketogenic amino acids. The process supplies energy to certain organs, particularly the brain, heart and skeletal muscle, under specific scenarios including fasting, caloric restriction, sleep, or others. (In rare metabolic diseases, insufficient gluconeogenesis can cause excessive ketogenesis and hypoglycemia, which may lead to the life-threatening condition known as non-diabetic ketoacidosis.)