sulfamethoxazole/trimethoprim
Also known as Co-trimoxazole, Trimethoprim, Sulfamethoxazole Drug Combination
Trimethoprim/sulfamethoxazole, sold under the trade names Bactrim, Cotrim (a short form of the British Approved Name, Co-trimoxazole) and Septra, among others, is a fixed-dose combination antibiotic medication used to treat a variety of bacterial infections. It consists of one part trimethoprim to five parts sulfamethoxazole. It is used to treat urinary tract infections, methicillin-resistant Staphylococcus aureus (MRSA) skin infections, travelers' diarrhea, respiratory tract infections, and cholera, among others. It is used both to treat and prevent pneumocystis pneumonia and toxoplasmosis in
Key facts
- Drug.verifiedrevid
- 388518461
- Drug.type
- combo
- Drug.image
- Trimethoprim and sulfamethoxazole.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 200
- Drug.caption
- Trimethoprim (top) and sulfamethoxazole (bottom)
- Drug.BAN
- Co-trimoxazole
- Drug.component1
- Sulfamethoxazole
- Drug.class1
- Sulfonamide antibiotic
- Drug.component2
- Trimethoprim
- Drug.class2
- Dihydrofolate reductase inhibitor
- Drug.tradename
- Bactrim, Cotrim, Septra, others
Article
15 sectionsContents
- Medical uses
- ''Pneumocystis jirovecii'' pneumonia
- Susceptibility
- Pregnancy and breast feeding
- Infants
- Adverse effects
- Contraindications
- Interactions
- Overdose
- Pharmacology
- Society and culture
- Legal status
- Brand names
- Economics
- References
Trimethoprim/sulfamethoxazole, sold under the trade names Bactrim, Cotrim (a short form of the British Approved Name, Co-trimoxazole) and Septra, among others, is a fixed-dose combination antibiotic medication used to treat a variety of bacterial infections. It consists of one part trimethoprim to five parts sulfamethoxazole. It is used to treat urinary tract infections, methicillin-resistant Staphylococcus aureus (MRSA) skin infections, travelers' diarrhea, respiratory tract infections, and cholera, among others. It is used both to treat and prevent pneumocystis pneumonia and toxoplasmosis in people with HIV/AIDS and other causes of immunosuppression. It can be given orally (swallowed by mouth) or intravenous infusion (slowly injected into a vein with an IV).
Trimethoprim/sulfamethoxazole is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. In 2023, it was the 128th most commonly prescribed medication in the United States, with more than 4million prescriptions.
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Acetaldehyde dehydrogenase inhibitorsChemical pages without DrugBank identifierCombination antibioticsDrugs developed by GSK plcDrugs developed by Hoffmann-La RocheDrugs developed by NovartisDrugs developed by PfizerDrugs that are a combination of chemicalsInfobox drug with local INN variantWorld Health Organization essential medicines