Skip to content

agonist

noun

  1. chemical substance which, upon binding to a receptor, leads to its activation
L227204 on Wikidata ↗

Wiktionary

Pronunciation: /ˈæɡəˌnɪst/ / /ˈeɪ̯ɡəˌnɪst/

noun

Etymology: Borrowed from Latin agōnista, from Ancient Greek ἀγωνιστής (agōnistḗs, “combatant, champion”). By surface analysis, agon or agony + -ist.

  1. Someone involved in a contest or battle (as in an agon), protagonist.
  2. The muscle that contracts while the other relaxes.

    When bending the elbow, the biceps is the agonist.

  3. A molecule that can combine with a receptor on a cell to produce a physiological reaction.

    Acetylcholine is an agonist at the cholinergic receptor.