dysregulation
noun
- The act of impairing a physiological regulatory mechanism
Wiktionary
noun
Etymology: Etymology tree Proto-Indo-European *dews-? Proto-Indo-European *dus- Proto-Hellenic *dus- Ancient Greek δῠσ- (dŭs-)der. New Latin dys-der. English dys- English regulation English dysregulation From dys- + regulation.
- A failure to regulate properly.
“For our purposes, it is sufficient to note that dysregulation of desquamatory protease activity in the SC is often involved in conditions of compromised skin barrier.”