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dysregulation

noun

  1. The act of impairing a physiological regulatory mechanism
L296453 on Wikidata ↗

Wiktionary

noun

Etymology: Etymology tree Proto-Indo-European *dews-? Proto-Indo-European *dus- Proto-Hellenic *dus- Ancient Greek δῠσ- (dŭs-)der. New Latin dys-der. English dys- English regulation English dysregulation From dys- + regulation.

  1. A failure to regulate properly.

    For our purposes, it is sufficient to note that dysregulation of desquamatory protease activity in the SC is often involved in conditions of compromised skin barrier.