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epimutation

noun

  1. a heritable change that does not affect the DNA sequence but results in a change in gene expression
L1451159 on Wikidata ↗

Wiktionary

Pronunciation: [ɛpɪmjuˈteɪʃən]

noun

Etymology: From epi- + mutation; compare epigenetic.

  1. A heritable change in gene expression that does not affect the actual base pair sequence of DNA.

    The first sign of cellular abnormality in some tumors is an epimutation—a change in heritable chromatin marks, such as an increase or decrease in the density of DNA methylation.