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Vinony

frameshift

noun

No English definition recorded for this entry.

L296143 on Wikidata ↗

Wiktionary

noun

Etymology: From frame + shift.

  1. A frameshift mutation.

verb

Etymology: From frame + shift.

  1. To use a starting point for translating a series of nucleotides that is off by an amount not divisible by three, resulting in an entirely distinct set of codons.

    “Commonly, there are stimulatory signals in mRNA distinct from the shift site that greatly increase the level of frameshifting at the shift site.”

    “Considering these costs, it seems likely that mechanisms may exist to stop frameshifted translation as soon as possible, depending on the frequency of occurrence.”