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methylation

noun

  1. process of adding a methyl group
L184873 on Wikidata ↗

Wiktionary

Pronunciation: /ˌmɛθɪˈleɪʃən/

noun

Etymology: Etymology tree Proto-Indo-European *médʰu Proto-Hellenic *métʰu Ancient Greek μέθυ (méthu) Proto-Indo-European *swel-der.? Ancient Greek ῡ̔́λη (hū́lē)der. German -yl German Methylbor. English methyl Proto-Indo-European *-tis Proto-Indo-European *-Hō Proto-Indo-European *-tiHō Proto-Italic *-tiō Latin -tiō Latin -ātiōlbor. Old French -ationbor. Middle English -acioun English -ation English methylation From methyl + -ation.

  1. The addition of a methyl group to a molecule.
  2. The addition of a methyl group to cytosine and adenine residues in DNA that leads to the epigenetic modification of DNA and the reduction of gene expression and protein production.