systemic

adj

Etymology: From system + -ic. Doublet of systematic.

1. Embedded within and spread throughout and affecting a whole system, group, body, economy, market, or society.

   “We can learn from the incidents found it the project database - looking at them and understanding what happened and what might have been done differently. We can see past errors, including systemic issues that required attention at managerial levels.”

2. Pertaining to an entire organism.

   “Iberdomide, a cereblon modulator promoting degradation of the transcription factors Ikaros and Aiolos, which affect leukocyte development and autoimmunity, is being evaluated for the treatment of systemic lupus erythematosus (SLE).”