topoisomerase

noun

class of enzymes

Wiktionary

Pronunciation: /ˌtɒpəʊˌaɪˈsɒməˌɹeɪs/ / /ˌtɑpoʊˌaɪˈsɑməˌɹeɪs/

noun

Etymology: Etymology tree Ancient Greek τόπος (tópos) English topo- English isomer Proto-Indo-European *dwóh₁ Proto-Indo-European *dwísder. Ancient Greek διά (diá) Ancient Greek δῐᾰ- (dĭă-) Proto-Indo-European *steh₂- Proto-Indo-European *stísteh₂ti Proto-Hellenic *hístāmi Ancient Greek ῐ̔́στημῐ (hĭ́stēmĭ) Ancient Greek δῐῐ̈́στημῐ (dĭĭ̈́stēmĭ) Ancient Greek δῐᾰ́στᾰσῐς (dĭắstăsĭs) English diastase English -ase English isomerase English topoisomerase From topo- + isomerase.

Any of several enzymes that affect the topology of DNA, especially ones that relax supercoiling.