1500 births

Holy Roman Emperor from 1519 to 1556 (1500–1558)

Florentine sculptor and goldsmith (1500–1571)

French noblewoman and courtier (1500-1566)

Spanish priest, Doctor of the Church

English cardinal, the last Roman Catholic Archbishop of Canterbury

Marquis and later first Duke of Mantua (1500-1540)

Italian artist (1500–1570)

German artist (1500-1550)

Spanish philosopher

Italian composer of the Renaissance

German humanist, polymath and poet (1500-1574)

Portuguese explorer

painter from the Northern Netherlands (1500–1560)

French artist (1500–1567)

Catholic cardinal

French painter, sculptor and engraver (ca. 1490-ca. 1560)

Bishop of London, was an English bishop

Spanish philosopher (1500-1591)

Spanish architect

English rebel

Spanish conquistador

French jurist (1500-1566)

Italian physician and botanist (1500-1555)

Italian artist (1500-1550)

German administrator of Passau and Salzburg, pledge lord of the County of Glatz (1500-1560)

Italian cardinal

French aristocrat

1500 - 23 May 1545

Italian humanist

Swiss writer (1500-1577)

Italian physician, botanist, and literary theorist (1500-1571)

German hymnwriter and poet

16th century Jewish Portuguese mystic

German conquistador

Christian mystic

Spanish scientist

Portuguese writer

Italian poet

Spanish conquistador

Last ruler of Jever from the Wiemken dynasty (1500-1575)

Duke of the Archipelago (r. 1517–1564)

Scottish theologian

French cleric

Bishop of Marsi, cardinal (1500-1552)

Italian Roman Catholic cardinal (1500-1566)

Spanish conquistador

Second Emperor of the Mạc dynasty

Italian cardinal

Italian condottiero (1500-1549)

16th-century Sufi master of the Shattari order and Sufi saint, a musician, and the author of Jawahir-i Khams

Wife of John Calvin

Czech bishop (1500–1572)

ruler of Portuguese India as governor

Italian cardinal (1500-1553)

Spanish sailor

Wali Sanga of Java

1st Margrave of Bergen (1500–1541)

German humanist

son of George Talbot, 4th Earl of Shrewsbury and Anne Hastings

painter (1500-1574)