1516 births

Queen of England and Ireland from 1553 to 1558

Swiss physician, bibliographer and naturalist (1516–1565)

16th-century English historian

Bayinnaung Kyawhtin Nawrahta; 16 January 1516 – 10 October 1581), personal name Maung Yeh Htut (ရှင်ရဲထွတ်), was King of Burma from 30 April 1550 until his death in 1581, during the Toungoo dynasty. His reign is considered one of the most momentous in Burmese history, famously described as "the greatest explosion of human energy ever seen in Burma". During his rule, he assembled the largest empire in Southeast Asian history, which encompassed much of present-day Myanmar, as well as the Shan States, Lan Na, Lan Xang, Manipur, and the Ayutthaya Kingdom.

Queen consort of Sweden

Regent of the Kazan Khanate (1516-1557)

German historian and humanist (1516 - 1580)

German nobleman; Duke of Jülich-Cleves-Berg (1516-1592)

Tabin-shwë-hti ( ; , ; 16 April 1516 – 30 April 1550), also called Black Tongue (လျှာနက်မင်း), was King of Burma from 1530 to 1550, and the founder of the First Toungoo Empire. His military campaigns (1534–1549) created the largest kingdom in Burma since the fall of the Pagan Empire in 1287. His administratively fragile kingdom proved to be the impetus for the eventual reunification of the entire country by his successor and brother-in-law Bayinnaung.

Grandfather of James VI and I, Regent of Scotland

French priest, writer and explorer (1516–1590)

third wife of Margrave George the Pious of Brandenburg-Ansbach

Safavid prince, governor and military officer

German poet, historian, and archaeologist, 1516-1571

Italian admiral

painter from Germany (1516-1573)

Italian cardinal (1516-1582)

Canon law historian (1517-1586)

Duke of Nevers

Italian theologian (1516-1590)

Portuguese noble

Polish writer

Count of Hohenzollern and Count of Haigerloch

French princess

Danish admiral

Spanish colonial administrator (1516-1576)

English noble

German cartographer of Silesia (1516–1574)

Khan of Kazan

Ming Dynasty empress

Italian painter (1516-1567)

Roman Catholic bishop

Marchese di Massa, son of Alfonso I d'Este and Lucrezia Borgia

Italian physician and philosopher

Finnish bishop

Italian humanist (1516-1567)

Italian cardinal

samurai

German banker and merchant (1516-1575)

Dutch writer

Italian architect (1516-1576)

Count of Nassau-Wiesbaden (1536-1566)

German theologian

French viscount

thumb|Portrait of Ōmandokoro, later known as Tenzui'in Ōmandokoro (大政所, 1516 – 29 August 1592) or Ōmandokoro Naka was the mother of the Japanese ruler Toyotomi Hideyoshi. She was also the mother of Asahi no kata, Tomo and Toyotomi Hidenaga.

King] of Ava Kingdom

(died 1569)

French army officer

Chinese statesman

German theologian

Italian condottiero

16th century English navigator, explorer and privateer

Italian Renaissance humanist (1516-1598)