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1539 deaths

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Guru Nanak
First Sikh Guru and founder of Sikhism
Isabella of Portugal
16th-century Holy Roman Empress and Queen of Spain (1503-1539)
Isabella d'Este
Italian noble
Thomas Boleyn, 1st Earl of Wiltshire
English diplomat and politician of the Tudor era (1477-1539)
Ayas Mehmed Paşa
Ottoman Grand Vizier
Ferdinand Columbus
Spanish bibliophile and cosmographer, the second son of Christopher Columbus (1488-1539)
George, Duke of Saxony
Duke of Saxony (1471-1539)
Anthony Maria Zaccaria
Italian saint
John III, Duke of Cleves
First ruler of the United Duchies of Jülich-Cleves-Berg
Il Pordenone
Italian painter (1484-1539)
Lorenzo Campeggio
Italian cardinal and politician
Ottaviano Petrucci
Italian printer
Ayşe Hatun
Consorte di Selim I
Bernardo Clesio
Catholic cardinal
Estevanico
Estevanico (–1539), Esteban de Dorantes and Estevanico the Moor, was the first African and person to explore North America and one of the last four survivors of the Narváez expedition.
Agnes Dürer
German model, wife of Albrecht Dürer
Lord Edmund Howard
16th-century English nobleman
Francesco Vettori
Italian diplomat (1474-1540)
Olbracht Gasztołd
Polish-Lithuanian noble
Johann Crotus
German writer
Ubaidullah
Shaybanid khan of Bukhara
Renée of Bourbon
Duchess consort of Lorraine
John Stone
(d. 1539) English Augustinian, Catholic saint and martyr
George IX of Kartli
king of Kartli
Marco Palmezzano
Italian renaissance painter (c.1460-1539)
Giacomo Simonetta
Italian cardinal
Nuno da Cunha
Portuguese colonial administrator
Adrian Fortescue
English Roman Catholic martyr
Henry Pole, 1st Baron Montagu
English nobleman executed for treason
María Enríquez de Luna
duchess of Gandía
Battista Spinola
Doge of Genoa
Gabriel Alonso de Herrera
Spanish agronomist (1470-1539)
Philip III, Count of Waldeck-Eisenberg
Count of Waldeck-Eisenberg
Floris van Egmont
Dutch stadtholder (1470-1539)
Zhang Cong
Ming dynasty politician
Andreas Althamer
German humanist
Johannes Lupi
franco-Flemish composer
Symphorien Champier
French physician
María de Salinas
Spanish noble
Johann Katzianer
Hungarian noble (1491-1539)
Philip, Prince of Portugal
Prince of Portugal
Francesco Chieregati
Roman Catholic bishop
Thomas Schöning
Archbishop of Riga (1500-1539)
Margaret Butler
Irish noblewoman
Nicholas Carew
English politician (1496-1539)
Sagipa
Sagipa or Zaquesazipa (died 1539, Bosa, New Kingdom of Granada) was the fifth and last ruler (psihipqua) of Muyquytá, currently known as Bogotá, as of 1537. He was the brother of his predecessor Bogotá but the traditional faction of the Muisca considered him an usurper as his nephew Chiayzaque, the cacique of Chía, was the legitimate successor of Tisquesusa. His hoa counterpart in the northern part of the Muisca territory was Quiminza, the last surviving ruler of the Muisca. The daughter of Sagipa, named as Magdalena de Guatavita, married conquistador Hernán Venegas Carrillo, one of the first
Katarzyna Weiglowa
Polish Jewish martyr
Cura Ocllo
Incan noble
Stjepan Brodarić
Croatian bishop and writer
James Beaton
Scottish church leader; (1473-1539)
John Righi
Italian saint
Anneke Esaiasdochter
Dutch heretic
Ilia Ostrogski
Polish noble
Fadrique de Portugal
Roman Catholic archbishop
Wang Ji
Ming physician, 1463-1539
Alonso Manso
Roman Catholic bishop
Gabriel von Salamanca-Ortenburg
general treasurer and archchancellor of an Austrian archduke in Spain (1489-1539)
Takayutpi
Thushin Takayutpi (, , or Taka Yut Pi or Taka Rat Pi; 1511–1539), also called Patira Rāja (ပတိရရာဇာ) was king of Hanthawaddy Pegu from 1526 to 1539. At his accession, the 15-year-old inherited the most prosperous and powerful kingdom of all post-Pagan kingdoms. But he never had control of his vassals who scarcely acknowledged him. A dozen years later, due to the young king's inexperience and mismanagement, the Mon-speaking kingdom founded in 1287 fell to a smaller Toungoo.
Conrad Goclenius
Renaissance humanist, and Latin scholar
Frederick, Hereditary Prince of Saxony
Saxon Royal (1504-1539)