4th-century BC regents

Olympias (; c. 375–316 BC) was an ancient Greek princess of the Molossians, the eldest daughter of King Neoptolemus I of Epirus, and the sister of Alexander I of Epirus. She was the mother of Alexander the Great by Philip II, king of Macedonia. She was extremely influential in Alexander's life and was recognized as de facto leader of Macedon during his conquests.

Antipater (; ;  400 BC319 BC) was a Macedonian general, regent and statesman under the successive kingships of Philip II of Macedon and his son, Alexander the Great. In the wake of the collapse of the Argead house, his son Cassander eventually ruled Macedonia as a king in his own right.

Cassander (; ; 355 BC – 297 BC) was king of the Ancient Greek kingdom of Macedonia from 305 BC until 297 BC, and de facto ruler of southern Greece from 317 BC until his death.

Perdiccas (, Perdikkas; 355BC – 320BC) was a Macedonian general, successor of Alexander the Great, and the regent of Alexander's empire after his death. When Alexander was dying, he entrusted his signet ring to Perdiccas. Initially the most pre-eminent of the successors, Perdiccas effectively ruled Alexander's increasingly unstable empire from Babylon for three years until his assassination, as the kings he ruled for were incapable.

4th-century BC Macedonian princess and queen regent of Epirus

Polyperchon (sometimes written Polysperchon; ; b. between 390–380 BC – d. after 304 BC, possibly into 3rd century BC), was a Macedonian Greek general who served both Philip II and Alexander the Great and then played an active role in the ensuing battles for control between Alexander's generals.

Peithon or Pithon (Greek: Πείθων or Πίθων, 355 – 314 BC) was the son of Crateuas, a nobleman from Eordaia in western Macedonia. He was famous for being one of the bodyguards of Alexander the Great, becoming the later satrap of Media, and claiming to be one of the diadochi.

regent of Macedon from 368 to 365 BC

Arrhidaeus or Arrhidaios ( lived 4th century BC), one of Alexander the Great's generals, was entrusted by Ptolemy to bring Alexander's body to Egypt in 323 BC, contrary to the wishes of Perdiccas who wanted the body sent to Macedonia. On the murder of Perdiccas in Egypt in 321 BC, Arrhidaeus and Peithon were appointed temporary commanders in chief, but through the intrigues of the queen Eurydice they were obliged to resign soon afterwards their office at Triparadisus in Northern Syria. On the division of the provinces which was decided by those attending Triparadisus, Arrhidaeus obtained the H

Sirras or Sirrhas (; d. 390 BC) was the son-in-law of the king of Lynkestis, Arrhabaeus ( 423–393 BC), having married his daughter Irra. He participated in an Illyrian-Lynkestian coalition's defeat of the attempted invasion of Lynkestis by the Macedonian king Archelaus. He may have been a Lynkestian prince-regent or an Illyrian chieftain, part of the Illyrian force in a previous and also successful Illyrian-Lynkestian coalition against Sparta and Macedon during the Peloponnesian War.

mythical queen regnant of the Britons

Concubine of King Huiwen of Qin (c. 338–265 BC)