Anesthetics

thumb|right|Leaves of the coca plant (Erythroxylum novogranatense var. Novogranatense), from which [[cocaine, a naturally occurring local anesthetic, is derived]] An anesthetic (American English) or anaesthetic (British English; see spelling differences) is a drug used to induce anesthesia ⁠— ⁠in other words, to result in a temporary loss of sensation or awareness. They may be divided into two broad classes: general anesthetics, which result in a reversible loss of consciousness, and local anesthetics, which cause a reversible loss of sensation for a limited region of the body without necessar

Trichloroethylene (TCE, IUPAC name: trichloroethene) is an organochloride with the formula C2HCl3, commonly used as an industrial degreaser. It is a clear, colourless, non-flammable, volatile liquid with a sweet chloroform-like pleasant mild smell and burning sweet taste. Trichloroethylene has been sold under a variety of trade names. Under the trade names Trimar and Trilene, it was used as a volatile anesthetic and as an inhaled obstetrical analgesic. Industrial abbreviations include trichlor, Trike, Tricky and tri. It should not be confused with the similar 1,1,1-trichloroethane, which was c

Embutramide (INN, USAN, BAN; brand name Embutane) is a potent sedative drug that is structurally related to GHB. It was developed by Hoechst A.G. in 1958 and was investigated as a general anesthetic agent, but was found to have a very narrow therapeutic window, with a 50 mg/kg dose producing effective sedation and a 75 mg/kg dose being fatal. Along with strong sedative effects, embutramide also produces respiratory depression and ventricular arrhythmia. Because of these properties, it was never adopted for medical use as an anesthetic as it was considered too dangerous for this purpo

chemical compound

Tenocyclidine (TCP) is a dissociative anesthetic with psychostimulant effects. It was discovered by a team at Parke-Davis in the late 1950s. It is similar in effects to phencyclidine (PCP) but is considerably more potent. TCP has slightly different binding properties to PCP, with more affinity for the NMDA receptors, but less affinity for the sigma receptors. Because of its high affinity for the PCP site of the NMDA receptor complex, the 3H radiolabelled form of TCP is widely used in research into NMDA receptors.

2,2,2-Tribromoethanol, often called just tribromoethanol, is a chemical compound with formula . Its molecule can be described as that of ethanol, with the three hydrogen atoms in position 2 (on the methyl group) replaced by bromine. It is a white crystalline solid, soluble in water and other solvents, that absorbs strongly in the UV below 290 nm.

General anesthesia method