Antipruritics

ZnO is a white powder insoluble in water

Menthol is a monoterpenoid organic compound that occurs naturally in the oils of certain plants in the mint family, such as corn mint and peppermint. It is a white or clear waxy crystalline substance that is solid at room temperature and melts slightly above. The main form of menthol occurring in nature is (−)-menthol, which is assigned the (1R,2S,5R) configuration.

aqueous solution of ammonia

Hydrocortisone is the name for the hormone cortisol when supplied as a medication. It is a corticosteroid and works as an anti-inflammatory and by immune suppression. Uses include conditions such as adrenocortical insufficiency, adrenogenital syndrome, high blood calcium, thyroiditis, rheumatoid arthritis, dermatitis, asthma, and COPD. It is the treatment of choice for adrenocortical insufficiency. It can be given by mouth, topically, rectally or by injection. Stopping treatment after long-term use should be done slowly.

Calamine, also known as calamine lotion, is a medication made from a combination of powdered zinc oxide and 0.5% ferric oxide (Fe2O3) that is used to treat mild itching. It benefits sunburn, insect bites, allergenic irritation, and other mild skin conditions, and may also help dry out secretions resulting from skin irritation. Its name comes from calamine, a historic name for the zinc ores smithsonite and hemimorphite.

Crotamiton is a drug that is used both as a scabicidal (for treating scabies) and as a general antipruritic (anti-itching drug). It is a lotion-based medicine that is applied to the whole body to get rid of the scabies mite that burrows under the skin and causes itching. It requires a prescription in the US.

therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System: Antipruritics, including antihistamines, anesthetics, etc.

Polidocanol is a local anaesthetic and antipruritic component of ointments and bath additives. It relieves itching caused by eczema and dry skin. It has also been used to treat varicose veins, hemangiomas, and vascular malformations. It is formed by the ethoxylation of dodecanol.

Antipruritics, abirritants, or anti-itch drugs, are medications that inhibit itching (Latin: pruritus). Itching is often associated with sunburns, allergic reactions, eczema, psoriasis, chickenpox, fungal infections, insect bites and stings like those from mosquitoes, fleas, mites, and contact dermatitis and urticaria caused by plants such as poison ivy (urushiol-induced contact dermatitis) or stinging nettle. Itching can also be caused by chronic kidney disease and related conditions.

astringent and antibacterial treatment

Nalfurafine (INN, USAN; brand name Remitch; former developmental code names TRK-820, AC-820, MT-9938) is an antipruritic (anti-itch drug) that is marketed in Japan for the treatment of uremic pruritus in individuals with chronic kidney disease undergoing hemodialysis. It activates the κ-opioid receptor (KOR) and is potent, selective, and centrally active. It was the first selective KOR agonist approved for clinical use. It has also been dubiously referred to as the "first non-narcotic opioid drug" in history.

Difelikefalin, sold under the brand name Korsuva, is an opioid peptide used for the treatment of moderate to severe itch. It acts as a peripherally-restricted, highly selective agonist of the κ-opioid receptor (KOR).