Category
page 2Benzoate esters
Pyr1
Pyr1 (LIMINIB) is an organic compound composed of carbon, hydrogen, oxygen and nitrogen that inhibits the enzyme LIM kinase.
tesetaxel
Tesetaxel is an orally administered taxane being investigated as a chemotherapy agent for various types of cancer, including breast cancer, gastric cancer, colorectal cancer, and other solid tumors. It differs from other members of the taxane class (e.g. paclitaxel or docetaxel) in that it is administered orally, not intravenously.
populin
Populin is a glucoside occurring in the bark, buds and leaves of certain species of poplar. The alkaline cleavage of populin produces benzoate and the glucoside salicin.
hexylcaine
Hexylcaine hydrochloride, also called cyclaine (Merck) or osmocaine, is a short-acting local anesthetic. It acts by inhibiting sodium channel conduction. Overdose can lead to headache, tinnitus, numbness and tingling around the mouth and tongue, convulsions, inability to breathe, and decreased heart function.
==Synthesis==
thumb|center|500px|Synthesis: Patent:
The reductive amination between 1-Amino-2-propanol [78-96-6] (1) and cyclohexanone gives 1-Cyclohexylamino-2-propanol [103-00-4] (2). Treatment with benzoyl chloride gives the ester, completing the synthesis of Hexylcaine (3).
pitofenone
Pitofenone is an antispasmodic.
flestolol
Flestolol is a short-acting beta adrenergic receptor antagonist.
dilazep
Dilazep is a vasodilator that acts as an adenosine reuptake inhibitor.